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Gene Expression Literature Summary
Symbol
Name
ID
Frs3
fibroblast growth factor receptor substrate 3
MGI:2135965

6 matching records from 6 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E7 E7.5 E8 E8.5 E9.5 E10.5 E11 E11.5 E12 E13.5 E14 E14.5 E15 E16 E16.5 E18 E18.5 E P
Immunohistochemistry (section) 1 1 1 1
In situ RNA (section) 1 1 1 1 2 1 1 1
In situ RNA (whole mount) 1 1 1 1
Western blot 1 1 1 1 1
RT-PCR 1 1 2 1 1 1 1
cDNA clones 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Frs3  fibroblast growth factor receptor substrate 3   (Synonyms: 4930417B13Rik, Frs2beta, MGC:25496, SNT2)
Results  Reference
3*J:226497 Brewer JR, Molotkov A, Mazot P, Hoch RV, Soriano P, Fgfr1 regulates development through the combinatorial use of signaling proteins. Genes Dev. 2015 Sep 1;29(17):1863-74
1J:108241 Desai J, Shannon ME, Johnson MD, Ruff DW, Hughes LA, Kerley MK, Carpenter DA, Johnson DK, Rinchik EM, Culiat CT, Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects. Hum Mol Genet. 2006 Apr 15;15(8):1329-41
1J:94724 Gotoh N, Ito M, Yamamoto S, Yoshino I, Song N, Wang Y, Lax I, Schlessinger J, Shibuya M, Lang RA, Tyrosine phosphorylation sites on FRS2alpha responsible for Shp2 recruitment are critical for induction of lens and retina. Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17144-9
6*J:89144 Gotoh N, Laks S, Nakashima M, Lax I, Schlessinger J, FRS2 family docking proteins with overlapping roles in activation of MAP kinase have distinct spatial-temporal patterns of expression of their transcripts. FEBS Lett. 2004 Apr 23;564(1-2):14-8
9J:157011 Hryciw T, MacDonald JI, Phillips R, Seah C, Pasternak S, Meakin SO, The fibroblast growth factor receptor substrate 3 adapter is a developmentally regulated microtubule-associated protein expressed in migrating and differentiated neurons. J Neurochem. 2010 Feb;112(4):924-39
11*J:69784 McDougall K, Kubu C, Verdi JM, Meakin SO, Developmental expression patterns of the signaling adapters FRS-2 and FRS-3 during early embryogenesis. Mech Dev. 2001 May;103(1-2):145-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory