Gene Expression Literature Summary

• Symbol: Hamp
• Name: hepcidin antimicrobial peptide
• ID: MGI:1933533

18 matching records from 18 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9.5	E10	E12	E13.5	E14.5	E15	E15.5	E16.5	E17	E17.5	E18	P
Immunohistochemistry (section)												1
In situ RNA (section)		1	1			1			1		1	2
Northern blot							1			1		1
Western blot								1				1
RT-PCR	2			2	1		1			2		12

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hamp  hepcidin antimicrobial peptide   (Synonyms: Hepc, HEPC1)
Results	Reference
1	J:236168 Arsenault PR, Song D, Chung YJ, Khurana TS, Lee FS, The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 Is Essential for Efficient Hydroxylation of Hypoxia-Inducible Factor alpha. Mol Cell Biol. 2016 Sep 15;36(18):2328-43
2	J:344220 Bai X, Wang B, Cui Y, Tian S, Zhang Y, You L, Chang YZ, Gao G, Hepcidin deficiency impairs hippocampal neurogenesis and mediates brain atrophy and memory decline in mice. J Neuroinflammation. 2024 Jan 9;21(1):15
1	J:331974 Cao C, Fleming MD, Loss of the placental iron exporter ferroportin 1 causes embryonic demise in late-gestation mouse pregnancy. Development. 2022 Dec 1;149(23):dev201160
1	J:329317 Chakraborty S, Andrieux G, Kastl P, Adlung L, Altamura S, Boehm ME, Schwarzmuller LE, Abdullah Y, Wagner MC, Helm B, Grone HJ, Lehmann WD, Boerries M, Busch H, Muckenthaler MU, Schilling M, Klingmuller U, Erythropoietin-driven dynamic proteome adaptations during erythropoiesis prevent iron overload in the developing embryo. Cell Rep. 2022 Sep 20;40(12):111360
1	J:157214 Iacovelli J, Mlodnicka AE, Veldman P, Ying GS, Dunaief JL, Schumacher A, Brain and retinal ferroportin 1 dysregulation in polycythaemia mice. Brain Res. 2009 Sep 15;1289:85-95
3	J:304067 Kammerer L, Mohammad G, Wolna M, Robbins PA, Lakhal-Littleton S, Fetal liver hepcidin secures iron stores in utero. Blood. 2020 Sep 24;136(13):1549-1557
1	J:216177 Labialle S, Marty V, Bortolin-Cavaille ML, Hoareau-Osman M, Pradere JP, Valet P, Martin PG, Cavaille J, The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation. EMBO J. 2014 Oct 1;33(19):2216-30
2	J:160796 Lee DH, Zhou LJ, Zhou Z, Xie JX, Jung JU, Liu Y, Xi CX, Mei L, Xiong WC, Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis. Blood. 2010 Apr 15;115(15):3136-45
1	J:98335 Mok H, Mendoza M, Prchal JT, Balogh P, Schumacher A, Dysregulation of ferroportin 1 interferes with spleen organogenesis in polycythaemia mice. Development. 2004 Oct;131(19):4871-81
1	J:176655 Moroishi T, Nishiyama M, Takeda Y, Iwai K, Nakayama KI, The FBXL5-IRP2 Axis Is Integral to Control of Iron Metabolism In Vivo. Cell Metab. 2011 Sep 7;14(3):339-51
4*	J:75776 Nicolas G, Bennoun M, Porteu A, Mativet S, Beaumont C, Grandchamp B, Sirito M, Sawadogo M, Kahn A, Vaulont S, Severe iron deficiency anemia in transgenic mice expressing liver hepcidin. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4596-601
1	J:141401 Okabe Y, Kawane K, Nagata S, IFN regulatory factor (IRF) 3/7-dependent and -independent gene induction by mammalian DNA that escapes degradation. Eur J Immunol. 2008 Nov;38(11):3150-8
7	J:140467 Scamuffa N, Basak A, Lalou C, Wargnier A, Marcinkiewicz J, Siegfried G, Chretien M, Calvo F, Seidah NG, Khatib AM, Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7. Gut. 2008 Nov;57(11):1573-82
2	J:190524 Shalom-Barak T, Zhang X, Chu T, Timothy Schaiff W, Reddy JK, Xu J, Sadovsky Y, Barak Y, Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
1*	J:272586 Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, Yamamoto T, Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019 Feb 15;146(4):dev168146
2	J:214455 Willemetz A, Lenoir A, Deschemin JC, Lopez-Otin C, Ramsay AJ, Vaulont S, Nicolas G, Matriptase-2 is essential for hepcidin repression during fetal life and postnatal development in mice to maintain iron homeostasis. Blood. 2014 Jul 17;124(3):441-4
1*	J:116886 Yoon D, Pastore YD, Divoky V, Liu E, Mlodnicka AE, Rainey K, Ponka P, Semenza GL, Schumacher A, Prchal JT, Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development. J Biol Chem. 2006 Sep 1;281(35):25703-11
1	J:301391 Yu Y, Jiang L, Wang H, Shen Z, Cheng Q, Zhang P, Wang J, Wu Q, Fang X, Duan L, Wang S, Wang K, An P, Shao T, Chung RT, Zheng S, Min J, Wang F, Hepatic transferrin plays a role in systemic iron homeostasis and liver ferroptosis. Blood. 2020 Aug 6;136(6):726-739