Gene Expression Literature Summary

• Symbol: Tln2
• Name: talin 2
• ID: MGI:1917799

14 matching records from 14 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E9	E9.5	E10	E12.5	E14.5	E15.5	E16	E18	E18.5	E	P
Immunohistochemistry (section)	1	1	1	1						2		4
In situ RNA (section)						1				1
Western blot					1			1	1	1	1	6
RT-PCR							1			1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tln2  talin 2   (Synonyms: mKIAA0320)
Results	Reference
3	J:153959 Conti FJ, Monkley SJ, Wood MR, Critchley DR, Muller U, Talin 1 and 2 are required for myoblast fusion, sarcomere assembly and the maintenance of myotendinous junctions. Development. 2009 Nov;136(21):3597-606
3*	J:190037 Debrand E, Conti FJ, Bate N, Spence L, Mazzeo D, Pritchard CA, Monkley SJ, Critchley DR, Mice carrying a complete deletion of the talin2 coding sequence are viable and fertile. Biochem Biophys Res Commun. 2012 Sep 21;426(2):190-5
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:209627 Kamiya K, Yum SW, Kurebayashi N, Muraki M, Ogawa K, Karasawa K, Miwa A, Guo X, Gotoh S, Sugitani Y, Yamanaka H, Ito-Kawashima S, Iizuka T, Sakurai T, Noda T, Minowa O, Ikeda K, Assembly of the cochlear gap junction macromolecular complex requires connexin 26. J Clin Invest. 2014 Apr 1;124(4):1598-607
1	J:159224 Kurosaka S, Leu NA, Zhang F, Bunte R, Saha S, Wang J, Guo C, He W, Kashina A, Arginylation-dependent neural crest cell migration is essential for mouse development. PLoS Genet. 2010;6(3):e1000878
1	J:200273 Legate KR, Montag D, Bottcher RT, Takahashi S, Fassler R, Comparative phenotypic analysis of the two major splice isoforms of phosphatidylinositol phosphate kinase type Igamma in vivo. J Cell Sci. 2012 Dec 1;125(Pt 23):5636-46
1	J:167114 Liang X, Sun Y, Ye M, Scimia MC, Cheng H, Martin J, Wang G, Rearden A, Wu C, Peterson KL, Powell HC, Evans SM, Chen J, Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality. Circulation. 2009 Aug 18;120(7):568-76
1	J:175092 Liu J, He X, Qi Y, Tian X, Monkley SJ, Critchley DR, Corbett SA, Lowry SF, Graham AM, Li S, Talin1 regulates integrin turnover to promote embryonic epithelial morphogenesis. Mol Cell Biol. 2011 Aug;31(16):3366-77
5*	J:195652 Manso AM, Li R, Monkley SJ, Cruz NM, Ong S, Lao DH, Koshman YE, Gu Y, Peterson KL, Chen J, Abel ED, Samarel AM, Critchley DR, Ross RS, Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload. J Biol Chem. 2013 Feb 8;288(6):4252-64
1*	J:81668 Menko AS, Kreidberg JA, Ryan TT, Van Bockstaele E, Kukuruzinska MA, Loss of alpha3beta1 integrin function results in an altered differentiation program in the mouse submandibular gland. Dev Dyn. 2001 Apr;220(4):337-49
1	J:168021 Monkley SJ, Kostourou V, Spence L, Petrich B, Coleman S, Ginsberg MH, Pritchard CA, Critchley DR, Endothelial cell talin1 is essential for embryonic angiogenesis. Dev Biol. 2011 Jan 15;349(2):494-502
1	J:69803 Palmer S, Groves N, Schindeler A, Yeoh T, Biben C, Wang CC, Sparrow DB, Barnett L, Jenkins NA, Copeland NG, Koentgen F, Mohun T, Harvey RP, The small muscle-specific protein Csl modifies cell shape and promotes myocyte fusion in an insulin-like growth factor 1-dependent manner. J Cell Biol. 2001 May 28;153(5):985-98
3	J:186606 Whitman SA, Cover C, Yu L, Nelson DL, Zarnescu DC, Gregorio CC, Desmoplakin and talin2 are novel mRNA targets of fragile X-related protein-1 in cardiac muscle. Circ Res. 2011 Jul 22;109(3):262-71
2	J:297072 Wurmser M, Chaverot N, Madani R, Sakai H, Negroni E, Demignon J, Saint-Pierre B, Mouly V, Amthor H, Tapscott S, Birchmeier C, Tajbakhsh S, Le Grand F, Sotiropoulos A, Maire P, SIX1 and SIX4 homeoproteins regulate PAX7+ progenitor cell properties during fetal epaxial myogenesis. Development. 2020 Oct 9;147(19):dev185975