Gene Expression Literature Summary

• Symbol: Ifitm3
• Name: interferon induced transmembrane protein 3
• ID: MGI:1913391

30 matching records from 30 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1.5	E2	E3.5	E5.5	E6	E6.5	E7	E7.5	E8	E8.5	E9	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15	E15.5	E17	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)							1	1	1	1	1	1				1		1							1
In situ RNA (section)						1	1	1	1		2	1	2					2					1			1
Immunohistochemistry (whole mount)									2	1
In situ RNA (whole mount)				1	1	3	6	4	8	3	3	2	2	1	1	1	1			1					2
In situ reporter (knock in)																1	1	1		1		1		1
Northern blot																						1				1
Western blot										1	1															1
RT-PCR	1	1	1		1		1		1	1					2	5	1		1	1	1	2		1		5

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ifitm3  interferon induced transmembrane protein 3   (Synonyms: 1110004C05Rik, Fgls, fragilis, IP15, mil-1)
Results	Reference
2	J:112799 Ben-Haim N, Lu C, Guzman-Ayala M, Pescatore L, Mesnard D, Bischofberger M, Naef F, Robertson EJ, Constam DB, The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4. Dev Cell. 2006 Sep;11(3):313-23
1*	J:190539 Bialecka M, Young T, Chuva de Sousa Lopes S, ten Berge D, Sanders A, Beck F, Deschamps J, Cdx2 contributes to the expansion of the early primordial germ cell population in the mouse. Dev Biol. 2012 Nov 15;371(2):227-34
1	J:112229 Bosman EA, Lawson KA, Debruyn J, Beek L, Francis A, Schoonjans L, Huylebroeck D, Zwijsen A, Smad5 determines murine amnion fate through the control of bone morphogenetic protein expression and signalling levels. Development. 2006 Sep;133(17):3399-409
1	J:91660 de Sousa Lopes SM, Roelen BA, Monteiro RM, Emmens R, Lin HY, Li E, Lawson KA, Mummery CL, BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo. Genes Dev. 2004 Aug 1;18(15):1838-49
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:155956 Feng W, Leach SM, Tipney H, Phang T, Geraci M, Spritz RA, Hunter LE, Williams T, Spatial and temporal analysis of gene expression during growth and fusion of the mouse facial prominences. PLoS One. 2009;4(12):e8066
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2	J:166677 Han DW, Tapia N, Joo JY, Greber B, Arauzo-Bravo MJ, Bernemann C, Ko K, Wu G, Stehling M, Do JT, Scholer HR, Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages. Cell. 2010 Nov 12;143(4):617-27
1	J:149220 Hara K, Kanai-Azuma M, Uemura M, Shitara H, Taya C, Yonekawa H, Kawakami H, Tsunekawa N, Kurohmaru M, Kanai Y, Evidence for crucial role of hindgut expansion in directing proper migration of primordial germ cells in mouse early embryogenesis. Dev Biol. 2009 Jun 15;330(2):427-39
1*	J:306307 Hoffmann S, Schmitteckert S, Raedecke K, Rheinert D, Diebold S, Roeth R, Weiss B, Granzow M, Niesler B, Griesbeck A, Eckstein V, Zimmermann WH, Just S, Rappold GA, Network-driven discovery yields new insight into Shox2-dependent cardiac rhythm control. Biochim Biophys Acta Gene Regul Mech. 2021 Apr-May;1864(4-5):194702
7*	J:137940 Lange UC, Adams DJ, Lee C, Barton S, Schneider R, Bradley A, Surani MA, Normal germ line establishment in mice carrying a deletion of the Ifitm/Fragilis gene family cluster. Mol Cell Biol. 2008 Aug;28(15):4688-96
10	J:87010 Lange UC, Saitou M, Western PS, Barton SC, Surani MA, The fragilis interferon-inducible gene family of transmembrane proteins is associated with germ cell specification in mice. BMC Dev Biol. 2003 Mar 19;3(1):1
1	J:344312 Liu H, Zhou R, Li S, Dong J, Fang Y, Luo Y, Su H, Lai B, Liang L, Zhang D, Zhang Y, Shyy JY, Zhou B, Yuan Z, Wang Y, Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development. iScience. 2024 Jan 19;27(1):108722
4	J:135354 Maeda C, Sato S, Hattori N, Tanaka S, Yagi S, Shiota K, DNA hypomethylation circuit of the mouse oocyte-specific histone h1foo gene in female germ cell lineage. Biol Reprod. 2008 May;78(5):816-21
9*	J:198561 Mikedis MM, Downs KM, Widespread but tissue-specific patterns of interferon-induced transmembrane protein 3 (IFITM3, FRAGILIS, MIL-1) in the mouse gastrula. Gene Expr Patterns. 2013 Oct;13(7):225-39
1*	J:241850 Naiman N, Fujioka K, Fujino M, Valerius MT, Potter SS, McMahon AP, Kobayashi A, Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 May 22;41(4):349-365.e3
7*	J:99994 Ohinata Y, Payer B, O'Carroll D, Ancelin K, Ono Y, Sano M, Barton SC, Obukhanych T, Nussenzweig M, Tarakhovsky A, Saitou M, Surani MA, Blimp1 is a critical determinant of the germ cell lineage in mice. Nature. 2005 Jul 14;436(7048):207-13
7	J:264160 Patoine A, Husseini A, Kasaai B, Gaumond MH, Moffatt P, The osteogenic cell surface marker BRIL/IFITM5 is dispensable for bone development and homeostasis in mice. PLoS One. 2017;12(9):e0184568
3	J:90707 Ropolo A, Tomasini R, Grasso D, Dusetti NJ, Cerquetti MC, Iovanna JL, Vaccaro MI, Cloning of IP15, a pancreatitis-induced gene whose expression inhibits cell growth. Biochem Biophys Res Commun. 2004 Jul 2;319(3):1001-9
7	J:78127 Saitou M, Barton SC, Surani MA, A molecular programme for the specification of germ cell fate in mice. Nature. 2002 Jul 18;418(6895):293-300
5	J:85862 Saitou M, Payer B, Lange UC, Erhardt S, Barton SC, Surani MA, Specification of germ cell fate in mice. Philos Trans R Soc Lond B Biol Sci. 2003 Aug 29;358(1436):1363-70
1*	J:225354 Sennett R, Wang Z, Rezza A, Grisanti L, Roitershtein N, Sicchio C, Mok KW, Heitman NJ, Clavel C, Ma'ayan A, Rendl M, An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin. Dev Cell. 2015 Sep 14;34(5):577-91
3*	J:235626 Sun J, Ting MC, Ishii M, Maxson R, Msx1 and Msx2 function together in the regulation of primordial germ cell migration in the mouse. Dev Biol. 2016 Sep 1;417(1):11-24
13*	J:82212 Tanaka SS, Matsui Y, Developmentally regulated expression of mil-1 and mil-2, mouse interferon-induced transmembrane protein like genes, during formation and differentiation of primordial germ cells. Mech Dev. 2002 Dec;119 Suppl 1:S261-7
2	J:199855 Tanaka SS, Nakane A, Yamaguchi YL, Terabayashi T, Abe T, Nakao K, Asashima M, Steiner KA, Tam PP, Nishinakamura R, Dullard/Ctdnep1 modulates WNT signalling activity for the formation of primordial germ cells in the mouse embryo. PLoS One. 2013;8(3):e57428
3	J:165423 Tanaka SS, Yamaguchi YL, Steiner KA, Nakano T, Nishinakamura R, Kwan KM, Behringer RR, Tam PP, Loss of Lhx1 activity impacts on the localization of primordial germ cells in the mouse. Dev Dyn. 2010 Nov;239(11):2851-9
1	J:104972 Tanaka SS, Yamaguchi YL, Tsoi B, Lickert H, Tam PP, IFITM/Mil/fragilis family proteins IFITM1 and IFITM3 play distinct roles in mouse primordial germ cell homing and repulsion. Dev Cell. 2005 Dec;9(6):745-56
2*	J:174767 Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA, Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
2	J:119483 Tang F, Kaneda M, O'Carroll D, Hajkova P, Barton SC, Sun YA, Lee C, Tarakhovsky A, Lao K, Surani MA, Maternal microRNAs are essential for mouse zygotic development. Genes Dev. 2007 Mar 15;21(6):644-8
2	J:277545 Wang Y, Li Q, Liu C, Han F, Chen M, Zhang L, Cui X, Qin Y, Bao S, Gao F, Protein arginine methyltransferase 5 (Prmt5) is required for germ cell survival during mouse embryonic development. Biol Reprod. 2015 Apr;92(4):104