Gene Expression Literature Summary

• Symbol: Carm1
• Name: coactivator-associated arginine methyltransferase 1
• ID: MGI:1913208

25 matching records from 25 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E2.5	E8.5	E9	E9.5	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14.5	E15	E15.5	E16.5	E17	E18.5	E19	P
Immunohistochemistry (section)																	1			4		4
In situ RNA (section)					1		1	1		1				1			2					2
Immunohistochemistry (whole mount)	2	2	2	2																		1
In situ RNA (whole mount)					1	1	4	4		3
Northern blot																						1
Western blot			1					1				1			1			1		2		3
RT-PCR	1	1	1		1			1			1	1	1	1		2		1	1	2	1	7
cDNA clones									2										1			1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Carm1  coactivator-associated arginine methyltransferase 1   (Synonyms: Prmt4)
Results	Reference
5*	J:265753 Bao J, Rousseaux S, Shen J, Lin K, Lu Y, Bedford MT, The arginine methyltransferase CARM1 represses p300*ACT*CREMtau activity and is required for spermiogenesis. Nucleic Acids Res. 2018 May 18;46(9):4327-4343
8*	J:153786 Bhattacherjee V, Horn KH, Singh S, Webb CL, Pisano MM, Greene RM, CBP/p300 and associated transcriptional co-activators exhibit distinct expression patterns during murine craniofacial and neural tube development. Int J Dev Biol. 2009;53(7):1097-104
3*	J:64957 Chen D, Ma H, Hong H, Koh SS, Huang SM, Schurter BT, Aswad DW, Stallcup MR, Regulation of transcription by a protein methyltransferase. Science. 1999 Jun 25;284(5423):2174-7
1	J:317822 Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poche RA, Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134
2	J:344642 de la Rosa S, Del Mar Rigual M, Vargiu P, Ortega S, Djouder N, Endogenous retroviruses shape pluripotency specification in mouse embryos. Sci Adv. 2024 Jan 26;10(4):eadk9394
1	J:177729 Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA, p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39
2	J:254851 Hatanaka Y, Tsusaka T, Shimizu N, Morita K, Suzuki T, Machida S, Satoh M, Honda A, Hirose M, Kamimura S, Ogonuki N, Nakamura T, Inoue K, Hosoi Y, Dohmae N, Nakano T, Kurumizaka H, Matsumoto K, Shinkai Y, Ogura A, Histone H3 Methylated at Arginine 17 Is Essential for Reprogramming the Paternal Genome in Zygotes. Cell Rep. 2017 Sep 19;20(12):2756-2765
4	J:269584 Hupalowska A, Jedrusik A, Zhu M, Bedford MT, Glover DM, Zernicka-Goetz M, CARM1 and Paraspeckles Regulate Pre-implantation Mouse Embryo Development. Cell. 2018 Dec 13;175(7):1902-1916.e13
3	J:153633 Ito T, Yadav N, Lee J, Furumatsu T, Yamashita S, Yoshida K, Taniguchi N, Hashimoto M, Tsuchiya M, Ozaki T, Lotz M, Bedford MT, Asahara H, Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification. BMC Dev Biol. 2009;9:47
3*	J:327081 Jamet S, Ha S, Ho TH, Houghtaling S, Timms A, Yu K, Paquette A, Maga AM, Greene NDE, Beier DR, The arginine methyltransferase Carm1 is necessary for heart development. G3 (Bethesda). 2022 Jul 29;12(8)
2*	J:159958 Kim D, Lee J, Cheng D, Li J, Carter C, Richie E, Bedford MT, Enzymatic activity is required for the in vivo functions of CARM1. J Biol Chem. 2010 Jan 8;285(2):1147-52
1	J:296989 Lim HYG, Alvarez YD, Gasnier M, Wang Y, Tetlak P, Bissiere S, Wang H, Biro M, Plachta N, Keratins are asymmetrically inherited fate determinants in the mammalian embryo. Nature. 2020 Sep;585(7825):404-409
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
4*	J:103446 McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA, A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14
2*	J:130227 Millien G, Beane J, Lenburg M, Tsao PN, Lu J, Spira A, Ramirez MI, Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction. Gene Expr Patterns. 2008 Jan;8(2):124-39
5	J:161950 O'Brien KB, Alberich-Jorda M, Yadav N, Kocher O, Diruscio A, Ebralidze A, Levantini E, Sng NJ, Bhasin M, Caron T, Kim D, Steidl U, Huang G, Halmos B, Rodig SJ, Bedford MT, Tenen DG, Kobayashi S, CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells. Development. 2010 Jul;137(13):2147-56
2*	J:191211 Sanchez G, Dury AY, Murray LM, Biondi O, Tadesse H, El Fatimy R, Kothary R, Charbonnier F, Khandjian EW, Cote J, A novel function for the survival motoneuron protein as a translational regulator. Hum Mol Genet. 2013 Feb 15;22(4):668-84
5	J:264087 Sato A, Kim JD, Mizukami H, Nakashima M, Kako K, Ishida J, Itakura A, Takeda S, Fukamizu A, Gestational changes in PRMT1 expression of murine placentas. Placenta. 2018 May;65:47-54
4*	J:209112 Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H, The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
1	J:226885 Tannour-Louet M, Han S, Louet JF, Zhang B, Romero K, Addai J, Sahin A, Cheung SW, Lamb DJ, Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action. Nat Med. 2014 Jul;20(7):715-24
4*	J:118236 Torres-Padilla ME, Parfitt DE, Kouzarides T, Zernicka-Goetz M, Histone arginine methylation regulates pluripotency in the early mouse embryo. Nature. 2007 Jan 11;445(7124):214-8
1	J:269583 Wang J, Wang L, Feng G, Wang Y, Li Y, Li X, Liu C, Jiao G, Huang C, Shi J, Zhou T, Chen Q, Liu Z, Li W, Zhou Q, Asymmetric Expression of LincGET Biases Cell Fate in Two-Cell Mouse Embryos. Cell. 2018 Dec 13;175(7):1887-1901.e18
2*	J:83623 Yadav N, Lee J, Kim J, Shen J, Hu MC, Aldaz CM, Bedford MT, Specific protein methylation defects and gene expression perturbations in coactivator-associated arginine methyltransferase 1-deficient mice. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6464-8
7	J:126896 Yildirim AO, Bulau P, Zakrzewicz D, Kitowska KE, Weissmann N, Grimminger F, Morty RE, Eickelberg O, Increased protein arginine methylation in chronic hypoxia: role of protein arginine methyltransferases. Am J Respir Cell Mol Biol. 2006 Oct;35(4):436-43
3*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48