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Gene Expression Literature Summary
Symbol
Name
ID
Snord116
small nucleolar RNA, C/D box 116 cluster
MGI:1891407

9 matching records from 9 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E7 E7.5 E9.5 E10.5 E11 E12.5 E13 E13.5 E15 E15.5 E17 E18.5 E P
In situ RNA (section) 1 1 1 1 1 1
In situ RNA (whole mount) 1 1
Northern blot 1 2 1 2 1 1 3
RT-PCR 1 2 1 4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Snord116  small nucleolar RNA, C/D box 116 cluster   (Synonyms: MBII-85, Pwcr1)
Results  Reference
4J:93285 Cavaille J, Seitz H, Paulsen M, Ferguson-Smith AC, Bachellerie JP, Identification of tandemly-repeated C/D snoRNA genes at the imprinted human 14q32 domain reminiscent of those at the Prader-Willi/Angelman syndrome region. Hum Mol Genet. 2002 Jul 15;11(13):1527-38
6*J:65556 de Los Santos T, Schweizer J, Rees CA, Francke U, Small evolutionarily conserved RNA, resembling C/D box small nucleolar RNA, is transcribed from PWCR1, a novel imprinted gene in the prader-willi deletion region, which Is highly expressed in brain. Am J Hum Genet. 2000 Nov;67(5):1067-82
6J:85656 Lee S, Walker CL, Wevrick R, Prader-Willi syndrome transcripts are expressed in phenotypically significant regions of the developing mouse brain. Gene Expr Patterns. 2003 Oct;3(5):599-609
4J:217174 Nakagaki A, Osanai H, Kishino T, Imprinting analysis of the mouse chromosome 7C region in DNMT1-null embryos. Gene. 2014 Dec 10;553(1):63-8
1J:112969 Ogawa H, Wu Q, Komiyama J, Obata Y, Kono T, Disruption of parental-specific expression of imprinted genes in uniparental fetuses. FEBS Lett. 2006 Oct 2;580(22):5377-84
1*J:152022 Skryabin BV, Gubar LV, Seeger B, Pfeiffer J, Handel S, Robeck T, Karpova E, Rozhdestvensky TS, Brosius J, Deletion of the MBII-85 snoRNA gene cluster in mice results in postnatal growth retardation. PLoS Genet. 2007 Dec 28;3(12):e235
1J:172308 Stefan M, Simmons RA, Bertera S, Trucco M, Esni F, Drain P, Nicholls RD, Global deficits in development, function, and gene expression in the endocrine pancreas in a deletion mouse model of Prader-Willi syndrome. Am J Physiol Endocrinol Metab. 2011 May;300(5):E909-22
1J:101829 Watrin F, Le Meur E, Roeckel N, Ripoche MA, Dandolo L, Muscatelli F, The Prader-Willi syndrome murine imprinting center is not involved in the spatio-temporal transcriptional regulation of the Necdin gene. BMC Genet. 2005 Jan 5;6(1):1
3J:320211 Zhang Q, Bouma GJ, McClellan K, Tobet S, Hypothalamic expression of snoRNA Snord116 is consistent with a link to the hyperphagia and obesity symptoms of Prader-Willi syndrome. Int J Dev Neurosci. 2012 Oct;30(6):479-85

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory