Gene Expression Literature Summary

• Symbol: Igf2bp1
• Name: insulin-like growth factor 2 mRNA binding protein 1
• ID: MGI:1890357

23 matching records from 23 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E4	E8.5	E9.5	E10.5	E11.5	E12.5	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E	P
Immunohistochemistry (section)						2	2			1		1		1		2	1	3
In situ RNA (section)						1	1	2	1	3			1	1				3
Immunohistochemistry (whole mount)		1																1
In situ RNA (whole mount)					2		2
In situ reporter (knock in)					2		2	1		2				1				1
Northern blot			1	1	1	1	2	1		1						1		1
Western blot	1	1					2			1						2		1
RT-PCR					1		5	3		3	2			1	2	1		8
cDNA clones															1			1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Igf2bp1  insulin-like growth factor 2 mRNA binding protein 1   (Synonyms: Crdbp, CRD-BP, D030026A21Rik, D11Moh40e, D11Moh45, IMP1, IMP-1, Zbp1)
Results	Reference
1*	J:91358 Brants JR, Ayoubi TA, Chada K, Marchal K, Van de Ven WJ, Petit MM, Differential regulation of the insulin-like growth factor II mRNA-binding protein genes by architectural transcription factor HMGA2. FEBS Lett. 2004 Jul 2;569(1-3):277-83
2*	J:103688 Challen G, Gardiner B, Caruana G, Kostoulias X, Martinez G, Crowe M, Taylor DF, Bertram J, Little M, Grimmond SM, Temporal and spatial transcriptional programs in murine kidney development. Physiol Genomics. 2005 Oct 17;23(2):159-71
1*	J:305415 Dai N, Rapley J, Angel M, Yanik MF, Blower MD, Avruch J, mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry. Genes Dev. 2011 Jun 1;25(11):1159-72
2*	J:235757 Degrauwe N, Schlumpf TB, Janiszewska M, Martin P, Cauderay A, Provero P, Riggi N, Suva ML, Paro R, Stamenkovic I, The RNA Binding Protein IMP2 Preserves Glioblastoma Stem Cells by Preventing let-7 Target Gene Silencing. Cell Rep. 2016 May 24;15(8):1634-47
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3	J:197462 Dillman AA, Hauser DN, Gibbs JR, Nalls MA, McCoy MK, Rudenko IN, Galter D, Cookson MR, mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex. Nat Neurosci. 2013 Apr;16(4):499-506
2	J:51219 Doyle GA, Betz NA, Leeds PF, Fleisig AJ, Prokipcak RD, Ross J, The c-myc coding region determinant-binding protein: a member of a family of KH domain RNA-binding proteins. Nucleic Acids Res. 1998 Nov 15;26(22):5036-44
1	J:223798 Golden EJ, Benito-Gonzalez A, Doetzlhofer A, The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3864-73
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
11*	J:100054 Hammer NA, Hansen TO, Byskov AG, Rajpert-De Meyts E, Grondahl ML, Bredkjaer HE, Wewer UM, Christiansen J, Nielsen FC, Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer. Reproduction. 2005 Aug;130(2):203-12
10*	J:89882 Hansen TV, Hammer NA, Nielsen J, Madsen M, Dalbaeck C, Wewer UM, Christiansen J, Nielsen FC, Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice. Mol Cell Biol. 2004 May;24(10):4448-64
5*	J:104317 Islam S, Montgomery RK, Fialkovich JJ, Grand RJ, Developmental and regional expression and localization of mRNAs encoding proteins involved in RNA translocation. J Histochem Cytochem. 2005 Dec;53(12):1501-9
2	J:291514 Lee J, Shin JE, Lee B, Kim H, Jeon Y, Ahn SH, Chi SW, Cho Y, The stem cell marker Prom1 promotes axon regeneration by down-regulating cholesterol synthesis via Smad signaling. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15955-15966
1*	J:239294 Lepelletier L, Langlois SD, Kent CB, Welshhans K, Morin S, Bassell GJ, Yam PT, Charron F, Sonic Hedgehog Guides Axons via Zipcode Binding Protein 1-Mediated Local Translation. J Neurosci. 2017 Feb 15;37(7):1685-1695
4*	J:103446 McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA, A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14
16*	J:52252 Nielsen J, Christiansen J, Lykke-Andersen J, Johnsen AH, Wewer UM, Nielsen FC, A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development. Mol Cell Biol. 1999 Feb;19(2):1262-70
13	J:207231 Nishino J, Kim S, Zhu Y, Zhu H, Morrison SJ, A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties. Elife. 2013;2:e00924
1*	J:328997 Nunez L, Buxbaum AR, Katz ZB, Lopez-Jones M, Nwokafor C, Czaplinski K, Pan F, Rosenberg J, Monday HR, Singer RH, Tagged actin mRNA dysregulation in IGF2BP1 -/- mice. Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2208465119
1*	J:235719 Preitner N, Quan J, Li X, Nielsen FC, Flanagan JG, IMP2 axonal localization, RNA interactome, and function in the development of axon trajectories. Development. 2016 Aug 1;143(15):2753-9
4*	J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
1	J:302089 Vezzali R, Weise SC, Hellbach N, Machado V, Heidrich S, Vogel T, The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons. Oncotarget. 2016 Jun 21;7(25):37436-37455
1*	J:174562 Welshhans K, Bassell GJ, Netrin-1-Induced Local beta-Actin Synthesis and Growth Cone Guidance Requires Zipcode Binding Protein 1. J Neurosci. 2011 Jul 6;31(27):9800-13
2*	J:117306 Xiao W, Liu W, Li Z, Liang D, Li L, White LD, Fox DA, Overbeek PA, Chen Q, Gene expression profiling in embryonic mouse lenses. Mol Vis. 2006;12:1692-8