Gene Expression Literature Summary

• Symbol: Grem2
• Name: gremlin 2, DAN family BMP antagonist
• ID: MGI:1344367

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E18.5	E	P
Immunohistochemistry (section)					1						1
In situ RNA (section)		2	1	2	1	3		1	1
In situ reporter (knock in)		1	1	1	1	1	1
Northern blot			1
RT-PCR	1		1	1	1		1			1	1
cDNA clones			1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Grem2  gremlin 2, DAN family BMP antagonist   (Synonyms: Prdc)
Results	Reference
3*	J:180958 Chi L, Saarela U, Railo A, Prunskaite-Hyyrylainen R, Skovorodkin I, Anthony S, Katsu K, Liu Y, Shan J, Salgueiro AM, Belo JA, Davies J, Yokouchi Y, Vainio SJ, A secreted BMP antagonist, Cer1, fine tunes the spatial organization of the ureteric bud tree during mouse kidney development. PLoS One. 2011;6(11):e27676
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:231595 Gurdziel K, Vogt KR, Walton KD, Schneider GK, Gumucio DL, Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun. Dev Dyn. 2016 May;245(5):614-26
1	J:284488 Huycke TR, Miller BM, Gill HK, Nerurkar NL, Sprinzak D, Mahadevan L, Tabin CJ, Genetic and Mechanical Regulation of Intestinal Smooth Muscle Development. Cell. 2019 Sep 19;179(1):90-105.e21
1*	J:144362 Ideno H, Takanabe R, Shimada A, Imaizumi K, Araki R, Abe M, Nifuji A, Protein related to DAN and cerberus (PRDC) inhibits osteoblastic differentiation and its suppression promotes osteogenesis in vitro. Exp Cell Res. 2009 Feb 1;315(3):474-84
1	J:342051 Koutsioumpa C, Santiago C, Jacobs K, Lehnert BP, Barrera V, Hutchinson JN, Schmelyun D, Lehoczky JA, Paul DL, Ginty DD, Skin-type-dependent development of murine mechanosensory neurons. Dev Cell. 2023 Oct 23;58(20):2032-2047.e6
1*	J:174506 Lai HC, Klisch TJ, Roberts R, Zoghbi HY, Johnson JE, In vivo neuronal subtype-specific targets of Atoh1 (Math1) in dorsal spinal cord. J Neurosci. 2011 Jul 27;31(30):10859-71
1	J:161852 Libusova L, Stemmler MP, Hierholzer A, Schwarz H, Kemler R, N-cadherin can structurally substitute for E-cadherin during intestinal development but leads to polyp formation. Development. 2010 Jul;137(14):2297-305
3	J:73145 Lu MM, Yang H, Zhang L, Shu W, Blair DG, Morrisey EE, The bone morphogenic protein antagonist gremlin regulates proximal-distal patterning of the lung. Dev Dyn. 2001 Dec;222(4):667-80
13*	J:48401 Minabe-Saegusa C, Saegusa H, Tsukahara M, Noguchi S, Sequence and expression of a novel mouse gene PRDC (protein related to DAN and cerberus) identified by a gene trap approach. Dev Growth Differ. 1998 Jun;40(3):343-53
1	J:143444 Park EJ, Watanabe Y, Smyth G, Miyagawa-Tomita S, Meyers E, Klingensmith J, Camenisch T, Buckingham M, Moon AM, An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart. Development. 2008 Nov;135(21):3599-610
1	J:341147 Young RE, Jones MK, Hines EA, Li R, Luo Y, Shi W, Verheyden JM, Sun X, Smooth Muscle Differentiation Is Essential for Airway Size, Tracheal Cartilage Segmentation, but Dispensable for Epithelial Branching. Dev Cell. 2020 Apr 6;53(1):73-85.e5