Gene Expression Literature Summary

• Symbol: Tjp2
• Name: tight junction protein 2
• ID: MGI:1341872

28 matching records from 28 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E2.5	E3	E3.5	E4	E7.5	E8	E8.5	E9.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E17.5	E19.5	E	P
Immunohistochemistry (section)					1	1	1	1	1	4	2	2	1	2	4		1	2	1		5
In situ RNA (section)															1	1					1
Immunohistochemistry (whole mount)	2	2	2	2	3	2					1									1	2
Western blot		1	1	1	1	1	1			1					2			2	2		1
RT-PCR		1		1	1	1					1						2				3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tjp2  tight junction protein 2   (Synonyms: ZO-2)
Results	Reference
1	J:220460 Andre P, Song H, Kim W, Kispert A, Yang Y, Wnt5a and Wnt11 regulate mammalian anterior-posterior axis elongation. Development. 2015 Apr 15;142(8):1516-27
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1	J:166833 Gladden AB, Hebert AM, Schneeberger EE, McClatchey AI, The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex. Dev Cell. 2010 Nov 16;19(5):727-39
1	J:220469 Grego-Bessa J, Hildebrand J, Anderson KV, Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains. Development. 2015 Apr 1;142(7):1305-14
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:181536 Harrelson Z, Kaestner KH, Evans SM, Foxa2 mediates critical functions of prechordal plate in patterning and morphogenesis and is cell autonomously required for early ventral endoderm morphogenesis. Biol Open. 2012;1:173-181
1	J:221347 Hubmacher D, Wang LW, Mecham RP, Reinhardt DP, Apte SS, Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia - a novel mouse model providing insights into geleophysic dysplasia. Dis Model Mech. 2015 May 1;8(5):487-99
1	J:173588 Kanazawa T, Ichii O, Otsuka S, Namiki Y, Hashimoto Y, Kon Y, Hepatocyte nuclear factor 4 alpha is associated with mesenchymal-epithelial transition in developing kidneys of C57BL/6 mice. J Vet Med Sci. 2011 May;73(5):601-7
5	J:222380 Katsuno T, Umeda K, Matsui T, Hata M, Tamura A, Itoh M, Takeuchi K, Fujimori T, Nabeshima Y, Noda T, Tsukita S, Tsukita S, Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells. Mol Biol Cell. 2008 Jun;19(6):2465-75
1	J:164765 Kokai E, Voss F, Fleischer F, Kempe S, Marinkovic D, Wolburg H, Leithauser F, Schmidt V, Deutsch U, Wirth T, Myc regulates embryonic vascular permeability and remodeling. Circ Res. 2009 May 22;104(10):1151-9
3	J:208053 Kopecki Z, Yang GN, Arkell RM, Jackson JE, Melville E, Iwata H, Ludwig RJ, Zillikens D, Murrell DF, Cowin AJ, Flightless I over-expression impairs skin barrier development, function and recovery following skin blistering. J Pathol. 2014 Apr;232(5):541-52
1	J:168023 Lahti L, Saarimaki-Vire J, Rita H, Partanen J, FGF signaling gradient maintains symmetrical proliferative divisions of midbrain neuronal progenitors. Dev Biol. 2011 Jan 15;349(2):270-82
1*	J:122548 Lee JD, Silva-Gagliardi NF, Tepass U, McGlade CJ, Anderson KV, The FERM protein Epb4.1l5 is required for organization of the neural plate and for the epithelial-mesenchymal transition at the primitive streak of the mouse embryo. Development. 2007 Jun;134(11):2007-16
1	J:244106 Lin C, Yao E, Zhang K, Jiang X, Croll S, Thompson-Peer K, Chuang PT, YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis. Elife. 2017 Mar 21;6:e21130
1	J:194042 Mahaffey JP, Grego-Bessa J, Liem KF Jr, Anderson KV, Cofilin and Vangl2 cooperate in the initiation of planar cell polarity in the mouse embryo. Development. 2013 Mar;140(6):1262-71
1	J:77501 Morita K, Furuse M, Yoshida Y, Itoh M, Sasaki H, Tsukita S, Miyachi Y, Molecular architecture of tight junctions of periderm differs from that of the maculae occludentes of epidermis. J Invest Dermatol. 2002 Jun;118(6):1073-9
1*	J:163834 Paudyal A, Damrau C, Patterson VL, Ermakov A, Formstone C, Lalanne Z, Wells S, Lu X, Norris DP, Dean CH, Henderson DJ, Murdoch JN, The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear. BMC Dev Biol. 2010;10:87
21*	J:143359 Sheth B, Nowak RL, Anderson R, Kwong WY, Papenbrock T, Fleming TP, Tight junction protein ZO-2 expression and relative function of ZO-1 and ZO-2 during mouse blastocyst formation. Exp Cell Res. 2008 Nov 1;314(18):3356-68
7*	J:81857 Unda FJ, Perez-Nanclares G, Le Morvan V, Hernandez C, Vilaxa A, De-la-Fuente M, Gorry P, Dynamic assembly of tight junction-associated proteins ZO-1, ZO-2, ZO-3 and occludin during mouse tooth development. Histol Histopathol. 2003 Jan;18(1):27-38
4*	J:169193 Walsh T, Pierce SB, Lenz DR, Brownstein Z, Dagan-Rosenfeld O, Shahin H, Roeb W, McCarthy S, Nord AS, Gordon CR, Ben-Neriah Z, Sebat J, Kanaan M, Lee MK, Frydman M, King MC, Avraham KB, Genomic duplication and overexpression of TJP2/ZO-2 leads to altered expression of apoptosis genes in progressive nonsyndromic hearing loss DFNA51. Am J Hum Genet. 2010 Jul 9;87(1):101-9
2*	J:136803 Wang H, Ding T, Brown N, Yamamoto Y, Prince LS, Reese J, Paria BC, Zonula occludens-1 (ZO-1) is involved in morula to blastocyst transformation in the mouse. Dev Biol. 2008 Jun 1;318(1):112-25
8*	J:175261 Wang H, Luan L, Ding T, Brown N, Reese J, Paria BC, Dynamics of zonula occludens-2 expression during preimplantation embryonic development in the hamster. Theriogenology. 2011 Sep 1;76(4):678-86
1	J:241749 Wilson SL, Wilson JP, Wang C, Wang B, McConnell SK, Primary cilia and Gli3 activity regulate cerebral cortical size. Dev Neurobiol. 2012 Sep;72(9):1196-212
1*	J:233398 Wu RC, Zeng Y, Pan IW, Wu MY, Androgen Receptor Coactivator ARID4B Is Required for the Function of Sertoli Cells in Spermatogenesis. Mol Endocrinol. 2015 Sep;29(9):1334-46
1	J:324178 Wu Y, Duan P, Wen Y, Zhang J, Wang X, Dong J, Zhao Q, Feng S, Lv C, Guo Y, Namekawa SH, Yuan S, UHRF1 establishes crosstalk between somatic and germ cells in male reproduction. Cell Death Dis. 2022 Apr 19;13(4):377
1	J:132649 Xu J, Kausalya PJ, Phua DC, Ali SM, Hossain Z, Hunziker W, Early embryonic lethality of mice lacking ZO-2, but Not ZO-3, reveals critical and nonredundant roles for individual zonula occludens proteins in mammalian development. Mol Cell Biol. 2008 Mar;28(5):1669-78
2	J:192804 Yates LL, Schnatwinkel C, Hazelwood L, Chessum L, Paudyal A, Hilton H, Romero MR, Wilde J, Bogani D, Sanderson J, Formstone C, Murdoch JN, Niswander LA, Greenfield A, Dean CH, Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung. Dev Biol. 2013 Jan 15;373(2):267-80
1	J:159690 Yates LL, Schnatwinkel C, Murdoch JN, Bogani D, Formstone CJ, Townsend S, Greenfield A, Niswander LA, Dean CH, The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis. Hum Mol Genet. 2010 Jun 1;19(11):2251-67