Gene Expression Literature Summary

• Symbol: St14
• Name: suppression of tumorigenicity 14 (colon carcinoma)
• ID: MGI:1338881

16 matching records from 16 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E2.5	E3	E3.5	E8	E8.5	E9	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E18.5	P
Immunohistochemistry (section)								1	1	2		1	2		1				3
In situ RNA (section)										1	1				2
Immunohistochemistry (whole mount)	1
In situ RNA (whole mount)								2	1	2	1
In situ reporter (knock in)							1	1	1	1	2				1	1	1		1
Western blot												1	1	1					1
RT-PCR	1	1	1	1	1	1		1		2		1		1		1		1	5
cDNA clones								1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

St14  suppression of tumorigenicity 14 (colon carcinoma)   (Synonyms: Epithin, matriptase, MT-SP1, Prss14, Tmprss14)
Results	Reference
8*	J:157446 Camerer E, Barker A, Duong DN, Ganesan R, Kataoka H, Cornelissen I, Darragh MR, Hussain A, Zheng YW, Srinivasan Y, Brown C, Xu SM, Regard JB, Lin CY, Craik CS, Kirchhofer D, Coughlin SR, Local protease signaling contributes to neural tube closure in the mouse embryo. Dev Cell. 2010 Jan 19;18(1):25-38
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
5*	J:118798 Fan B, Brennan J, Grant D, Peale F, Rangell L, Kirchhofer D, Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth. Dev Biol. 2007 Mar 1;303(1):222-30
6*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
8*	J:98180 Khang I, Sonn S, Park JH, Rhee K, Park D, Kim K, Expression of epithin in mouse preimplantation development: Its functional role in compaction. Dev Biol. 2005 May 1;281(1):134-44
1*	J:105558 Kim TS, Heinlein C, Hackman RC, Nelson PS, Phenotypic analysis of mice lacking the Tmprss2-encoded protease. Mol Cell Biol. 2006 Feb;26(3):965-75
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:143429 Nagaike K, Kawaguchi M, Takeda N, Fukushima T, Sawaguchi A, Kohama K, Setoyama M, Kataoka H, Defect of hepatocyte growth factor activator inhibitor type 1/serine protease inhibitor, Kunitz type 1 (Hai-1/Spint1) leads to ichthyosis-like condition and abnormal hair development in mice. Am J Pathol. 2008 Nov;173(5):1464-75
1	J:161350 Nath AK, Krauthammer M, Li P, Davidov E, Butler LC, Copel J, Katajamaa M, Oresic M, Buhimschi I, Buhimschi C, Snyder M, Madri JA, Proteomic-based detection of a protein cluster dysregulated during cardiovascular development identifies biomarkers of congenital heart defects. PLoS One. 2009;4(1):e4221
4	J:117240 Netzel-Arnett S, Currie BM, Szabo R, Lin CY, Chen LM, Chai KX, Antalis TM, Bugge TH, List K, Evidence for a matriptase-prostasin proteolytic cascade regulating terminal epidermal differentiation. J Biol Chem. 2006 Nov 3;281(44):32941-5
2*	J:122516 Sherwood RI, Jitianu C, Cleaver O, Shaywitz DA, Lamenzo JO, Chen AE, Golub TR, Melton DA, Prospective isolation and global gene expression analysis of definitive and visceral endoderm. Dev Biol. 2007 Apr 15;304(2):541-55
3*	J:152846 Szabo R, Hobson JP, Christoph K, Kosa P, List K, Bugge TH, Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice. Development. 2009 Aug;136(15):2653-63
3*	J:235722 Szabo R, Lantsman T, Peters DE, Bugge TH, Delineation of proteolytic and non-proteolytic functions of the membrane-anchored serine protease prostasin. Development. 2016 Aug 1;143(15):2818-28
4	J:142708 Szabo R, Molinolo A, List K, Bugge TH, Matriptase inhibition by hepatocyte growth factor activator inhibitor-1 is essential for placental development. Oncogene. 2007 Mar 8;26(11):1546-56
5	J:221394 Szabo R, Peters DE, Kosa P, Camerer E, Bugge TH, Regulation of feto-maternal barrier by matriptase- and PAR-2-mediated signaling is required for placental morphogenesis and mouse embryonic survival. PLoS Genet. 2014 Jul;10(7):e1004470
2	J:188121 Szabo R, Uzzun Sales K, Kosa P, Shylo NA, Godiksen S, Hansen KK, Friis S, Gutkind JS, Vogel LK, Hummler E, Camerer E, Bugge TH, Reduced Prostasin (CAP1/PRSS8) Activity Eliminates HAI-1 and HAI-2 Deficiency-Associated Developmental Defects by Preventing Matriptase Activation. PLoS Genet. 2012 Aug;8(8):e1002937