Gene Expression Literature Summary

• Symbol: Slc40a1
• Name: solute carrier family 40 (iron-regulated transporter), member 1
• ID: MGI:1315204

25 matching records from 25 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7	E7.5	E8.5	E9.5	E10	E11.5	E12.5	E13.5	E14	E14.5	E15.5	E16	E16.5	E17.5	E18.5	P
Immunohistochemistry (section)		1			1	1	1		1	1		2	1		1		12
In situ RNA (section)							1	1	2		2	1				1	2
In situ RNA (whole mount)			1	1
In situ reporter (knock in)	1		1	1	1												2
Northern blot																	3
Western blot												1		1	2		8
RT-PCR					1				2			2		2	1		7
cDNA clones												1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Slc40a1  solute carrier family 40 (iron-regulated transporter), member 1   (Synonyms: Dusg, ferroportin1, FPN1, IREG1, metal transporting protein 1, MTP1, Ol5, Pcm, Slc11a3)
Results	Reference
5	J:63027 Abboud S, Haile DJ, A novel mammalian iron-regulated protein involved in intracellular iron metabolism. J Biol Chem. 2000 Jun 30;275(26):19906-12
5	J:331974 Cao C, Fleming MD, Loss of the placental iron exporter ferroportin 1 causes embryonic demise in late-gestation mouse pregnancy. Development. 2022 Dec 1;149(23):dev201160
4	J:329317 Chakraborty S, Andrieux G, Kastl P, Adlung L, Altamura S, Boehm ME, Schwarzmuller LE, Abdullah Y, Wagner MC, Helm B, Grone HJ, Lehmann WD, Boerries M, Busch H, Muckenthaler MU, Schilling M, Klingmuller U, Erythropoietin-driven dynamic proteome adaptations during erythropoiesis prevent iron overload in the developing embryo. Cell Rep. 2022 Sep 20;40(12):111360
2*	J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
3	J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
4	J:60557 Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer A, Barut B, Zapata A, Law TC, Brugnara C, Lux SE, Pinkus GS, Pinkus JL, Kingsley PD, Palis J, Fleming MD, Andrews NC, Zon LI, Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter [see comments]. Nature. 2000 Feb 17;403(6771):776-81
1*	J:129846 Donovan A, Lima CA, Pinkus JL, Pinkus GS, Zon LI, Robine S, Andrews NC, The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metab. 2005 Mar;1(3):191-200
2	J:317814 Fan L, Ou YJ, Zhu YX, Liang YD, Zhou Y, Wang YN, Lif Deficiency Leads to Iron Transportation Dysfunction in Ameloblasts. J Dent Res. 2022 Jan;101(1):63-72
1*	J:161785 Gu WX, Kania A, Identification of genes controlled by LMX1B in E13.5 mouse limbs. Dev Dyn. 2010 Aug;239(8):2246-55
3	J:157214 Iacovelli J, Mlodnicka AE, Veldman P, Ying GS, Dunaief JL, Schumacher A, Brain and retinal ferroportin 1 dysregulation in polycythaemia mice. Brain Res. 2009 Sep 15;1289:85-95
5	J:304067 Kammerer L, Mohammad G, Wolna M, Robbins PA, Lakhal-Littleton S, Fetal liver hepcidin secures iron stores in utero. Blood. 2020 Sep 24;136(13):1549-1557
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:67313 LaVaute T, Smith S, Cooperman S, Iwai K, Land W, Meyron-Holtz E, Drake SK, Miller G, Abu-Asab M, Tsokos M, Switzer R, Grinberg A, Love P, Tresser N, Rouault TA, Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice. Nat Genet. 2001 Feb;27(2):209-14
2	J:160796 Lee DH, Zhou LJ, Zhou Z, Xie JX, Jung JU, Liu Y, Xi CX, Mei L, Xiong WC, Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis. Blood. 2010 Apr 15;115(15):3136-45
6	J:164587 Mao J, McKean DM, Warrier S, Corbin JG, Niswander L, Zohn IE, The iron exporter ferroportin 1 is essential for development of the mouse embryo, forebrain patterning and neural tube closure. Development. 2010 Sep;137(18):3079-88
7	J:98335 Mok H, Mendoza M, Prchal JT, Balogh P, Schumacher A, Dysregulation of ferroportin 1 interferes with spleen organogenesis in polycythaemia mice. Development. 2004 Oct;131(19):4871-81
1	J:176655 Moroishi T, Nishiyama M, Takeda Y, Iwai K, Nakayama KI, The FBXL5-IRP2 Axis Is Integral to Control of Iron Metabolism In Vivo. Cell Metab. 2011 Sep 7;14(3):339-51
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
3	J:220468 Walentin K, Hinze C, Werth M, Haase N, Varma S, Morell R, Aue A, Potschke E, Warburton D, Qiu A, Barasch J, Purfurst B, Dieterich C, Popova E, Bader M, Dechend R, Staff AC, Yurtdas ZY, Kilic E, Schmidt-Ott KM, A Grhl2-dependent gene network controls trophoblast branching morphogenesis. Development. 2015 Mar 15;142(6):1125-36
1	J:64018 Wang CC, Biben C, Robb L, Nassir F, Barnett L, Davidson NO, Koentgen F, Tarlinton D, Harvey RP, Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera. Dev Biol. 2000 Aug 15;224(2):152-67
3	J:214455 Willemetz A, Lenoir A, Deschemin JC, Lopez-Otin C, Ramsay AJ, Vaulont S, Nicolas G, Matriptase-2 is essential for hepcidin repression during fetal life and postnatal development in mice to maintain iron homeostasis. Blood. 2014 Jul 17;124(3):441-4
2*	J:116886 Yoon D, Pastore YD, Divoky V, Liu E, Mlodnicka AE, Rainey K, Ponka P, Semenza GL, Schumacher A, Prchal JT, Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development. J Biol Chem. 2006 Sep 1;281(35):25703-11
2	J:301391 Yu Y, Jiang L, Wang H, Shen Z, Cheng Q, Zhang P, Wang J, Wu Q, Fang X, Duan L, Wang S, Wang K, An P, Shao T, Chung RT, Zheng S, Min J, Wang F, Hepatic transferrin plays a role in systemic iron homeostasis and liver ferroptosis. Blood. 2020 Aug 6;136(6):726-739
1	J:330612 Zheng X, Huang W, He Z, Li Y, Li S, Song Y, Effects of Fam83h truncation mutation on enamel developmental defects in male C57/BL6J mice. Bone. 2022 Oct 20;166:116595