Gene Expression Literature Summary

• Symbol: Vamp2
• Name: vesicle-associated membrane protein 2
• ID: MGI:1313277

39 matching records from 39 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E11	E11.5	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	P
Immunohistochemistry (section)	1				1					1	1			1	2	6
In situ RNA (section)		1					2		1				1			2
Western blot			1	1		2	1	4				2	2	4	2	17
RT-PCR			1	1												4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Vamp2  vesicle-associated membrane protein 2   (Synonyms: Syb2, Syb-2, sybII, synaptobrevin-2, synaptobrevin II)
Results	Reference
6*	J:36947 Ahnert-Hilger G, Kutay U, Chahoud I, Rapoport T, Wiedenmann B, Synaptobrevin is essential for secretion but not for the development of synaptic processes. Eur J Cell Biol. 1996 May;70(1):1-11
1*	J:243971 Arnold M, Cross R, Singleton KS, Zlatic S, Chapleau C, Mullin AP, Rolle I, Moore CC, Theibert A, Pozzo-Miller L, Faundez V, Larimore J, The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin. Front Cell Neurosci. 2016;10:218
1	J:231655 Barber M, Arai Y, Morishita Y, Vigier L, Causeret F, Borello U, Ledonne F, Coppola E, Contremoulins V, Pfrieger FW, Tissir F, Govindan S, Jabaudon D, Proux-Gillardeaux V, Galli T, Pierani A, Migration Speed of Cajal-Retzius Cells Modulated by Vesicular Trafficking Controls the Size of Higher-Order Cortical Areas. Curr Biol. 2015 Oct 5;25(19):2466-78
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1*	J:142647 Best D, Adams IR, Sdmg1 is a component of secretory granules in mouse secretory exocrine tissues. Dev Dyn. 2008 Dec 18;238(1):223-231
2	J:89658 Bolis A, Corbetta S, Cioce A, de Curtis I, Differential distribution of Rac1 and Rac3 GTPases in the developing mouse brain: implications for a role of Rac3 in Purkinje cell differentiation. Eur J Neurosci. 2003 Nov;18(9):2417-24
3*	J:100913 Borisovska M, Zhao Y, Tsytsyura Y, Glyvuk N, Takamori S, Matti U, Rettig J, Sudhof T, Bruns D, v-SNAREs control exocytosis of vesicles from priming to fusion. EMBO J. 2005 Jun 15;24(12):2114-26
2*	J:91381 Bouwman J, Maia AS, Camoletto PG, Posthuma G, Roubos EW, Oorschot VM, Klumperman J, Verhage M, Quantification of synapse formation and maintenance in vivo in the absence of synaptic release. Neuroscience. 2004;126(1):115-26
2	J:207646 Cotrufo T, Andres RM, Ros O, Perez-Branguli F, Muhaisen A, Fuschini G, Martinez R, Pascual M, Comella JX, Soriano E, Syntaxin 1 is required for DCC/Netrin-1-dependent chemoattraction of migrating neurons from the lower rhombic lip. Eur J Neurosci. 2012 Nov;36(9):3152-64
2	J:177410 Cotrufo T, Perez-Branguli F, Muhaisen A, Ros O, Andres R, Baeriswyl T, Fuschini G, Tarrago T, Pascual M, Urena J, Blasi J, Giralt E, Stoeckli ET, Soriano E, A Signaling Mechanism Coupling Netrin-1/Deleted in Colorectal Cancer Chemoattraction to SNARE-Mediated Exocytosis in Axonal Growth Cones. J Neurosci. 2011 Oct 12;31(41):14463-14480
2	J:124043 Deng DR, Djalali S, Holtje M, Grosse G, Stroh T, Voigt I, Kusserow H, Theuring F, Ahnert-Hilger G, Hortnagl H, Embryonic and postnatal development of the serotonergic raphe system and its target regions in 5-HT1A receptor deletion or overexpressing mouse mutants. Neuroscience. 2007 Jun 29;147(2):388-402
1	J:105301 Deuel TA, Liu JS, Corbo JC, Yoo SY, Rorke-Adams LB, Walsh CA, Genetic interactions between doublecortin and doublecortin-like kinase in neuronal migration and axon outgrowth. Neuron. 2006 Jan 5;49(1):41-53
2*	J:315751 Fuschini G, Cotrufo T, Ros O, Muhaisen A, Andres R, Comella JX, Soriano E, Syntaxin-1/TI-VAMP SNAREs interact with Trk receptors and are required for neurotrophin-dependent outgrowth. Oncotarget. 2018 Nov 13;9(89):35922-35940
1	J:263474 Geerts CJ, Plomp JJ, Koopmans B, Loos M, van der Pijl EM, van der Valk MA, Verhage M, Groffen AJ, Tomosyn-2 is required for normal motor performance in mice and sustains neurotransmission at motor endplates. Brain Struct Funct. 2015 Jul;220(4):1971-82
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:238301 Henley KD, Stanescu DE, Kropp PA, Wright CV, Won KJ, Stoffers DA, Gannon M, Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and beta-Cell Function. Cell Rep. 2016 Jun 21;15(12):2637-50
1*	J:114576 Holt M, Varoqueaux F, Wiederhold K, Takamori S, Urlaub H, Fasshauer D, Jahn R, Identification of SNAP-47, a novel Qbc-SNARE with ubiquitous expression. J Biol Chem. 2006 Jun 23;281(25):17076-83
1	J:171817 Huang G, Ge G, Wang D, Gopalakrishnan B, Butz DH, Colman RJ, Nagy A, Greenspan DS, alpha3(V) collagen is critical for glucose homeostasis in mice due to effects in pancreatic islets and peripheral tissues. J Clin Invest. 2011 Feb 1;121(2):769-83
1	J:131843 Jamain S, Radyushkin K, Hammerschmidt K, Granon S, Boretius S, Varoqueaux F, Ramanantsoa N, Gallego J, Ronnenberg A, Winter D, Frahm J, Fischer J, Bourgeron T, Ehrenreich H, Brose N, Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1710-5
1	J:308815 Larimore J, Zlatic SA, Arnold M, Singleton KS, Cross R, Rudolph H, Bruegge MV, Sweetman A, Garza C, Whisnant E, Faundez V, Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus. Front Genet. 2017;8:28
2	J:284900 Larsen R, Proue A, Scott EP, Christiansen M, Nakagawa Y, The Thalamus Regulates Retinoic Acid Signaling and Development of Parvalbumin Interneurons in Postnatal Mouse Prefrontal Cortex. eNeuro. 2019 Jan-Feb;6(1):ENEURO.0018-19.2019
1	J:221387 Liu L, Fujino K, Nishimura M, Pre-synaptic localization of the gamma-secretase-inhibiting protein p24alpha2 in the mammalian brain. J Neurochem. 2015 May;133(3):422-31
1	J:236499 Liu L, Watanabe N, Akatsu H, Nishimura M, Neuronal expression of ILEI/FAM3C and its reduction in Alzheimer's disease. Neuroscience. 2016 Aug 25;330:236-46
3	J:278342 Liu Y, Sugiura Y, Sudhof TC, Lin W, Ablation of All Synaptobrevin vSNAREs Blocks Evoked But Not Spontaneous Neurotransmitter Release at Neuromuscular Synapses. J Neurosci. 2019 Jul 31;39(31):6049-6066
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
2*	J:84539 Peng XR, Jia Z, Zhang Y, Ware J, Trimble WS, The septin CDCrel-1 is dispensable for normal development and neurotransmitter release. Mol Cell Biol. 2002 Jan;22(1):378-87
1	J:72798 Pin CL, Rukstalis JM, Johnson C, Konieczny SF, The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity. J Cell Biol. 2001 Nov 12;155(4):519-30
1*	J:165469 Sadakata T, Itakura M, Kozaki S, Sekine Y, Takahashi M, Furuichi T, Differential distributions of the Ca2+ -dependent activator protein for secretion family proteins (CAPS2 and CAPS1) in the mouse brain. J Comp Neurol. 2006 Apr 20;495(6):735-53
1	J:87385 Sadakata T, Mizoguchi A, Sato Y, Katoh-Semba R, Fukuda M, Mikoshiba K, Furuichi T, The secretory granule-associated protein CAPS2 regulates neurotrophin release and cell survival. J Neurosci. 2004 Jan 7;24(1):43-52
1	J:326958 Sapir T, Kshirsagar A, Gorelik A, Olender T, Porat Z, Scheffer IE, Goldstein DB, Devinsky O, Reiner O, Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex. Nat Commun. 2022 Jul 21;13(1):4209
1	J:255335 Tan GH, Liu YY, Wang L, Li K, Zhang ZQ, Li HF, Yang ZF, Li Y, Li D, Wu MY, Yu CL, Long JJ, Chen RC, Li LX, Yin LP, Liu JW, Cheng XW, Shen Q, Shu YS, Sakimura K, Liao LJ, Wu ZY, Xiong ZQ, PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum. Cell Res. 2018 Jan;28(1):90-110
1	J:99424 Toonen RF, de Vries KJ, Zalm R, Sudhof TC, Verhage M, Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation. J Neurochem. 2005 Jun;93(6):1393-400
1	J:234628 Vardar G, Chang S, Arancillo M, Wu YJ, Trimbuch T, Rosenmund C, Distinct Functions of Syntaxin-1 in Neuronal Maintenance, Synaptic Vesicle Docking, and Fusion in Mouse Neurons. J Neurosci. 2016 Jul 27;36(30):7911-24
1	J:77237 Verhage M, Maia AS, Plomp JJ, Brussaard AB, Heeroma JH, Vermeer H, Toonen RF, Hammer RE, van den Berg TK, Missler M, Geuze HJ, Sudhof TC, Synaptic assembly of the brain in the absence of neurotransmitter secretion. Science. 2000 Feb 4;287(5454):864-9
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1	J:73755 Washbourne P, Thompson PM, Carta M, Costa ET, Mathews JR, Lopez-Bendito G, Molnar Z, Becher MW, Valenzuela CF, Partridge LD, Wilson MC, Genetic ablation of the t-SNARE SNAP-25 distinguishes mechanisms of neuroexocytosis. Nat Neurosci. 2002 Jan;5(1):19-26
1	J:278320 Wolter S, Mohrle D, Schmidt H, Pfeiffer S, Zelle D, Eckert P, Kramer M, Feil R, Pilz PKD, Knipper M, Ruttiger L, GC-B Deficient Mice With Axon Bifurcation Loss Exhibit Compromised Auditory Processing. Front Neural Circuits. 2018;12:65
3	J:184828 Yap K, Lim ZQ, Khandelia P, Friedman B, Makeyev EV, Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention. Genes Dev. 2012 Jun 1;26(11):1209-23
2	J:180658 Zylbersztejn K, Petkovic M, Burgo A, Deck M, Garel S, Marcos S, Bloch-Gallego E, Nothias F, Serini G, Bagnard D, Binz T, Galli T, The vesicular SNARE Synaptobrevin is required for Semaphorin 3A axonal repulsion. J Cell Biol. 2012 Jan 9;196(1):37-46