Gene Expression Literature Summary

• Symbol: Cidea
• Name: cell death-inducing DNA fragmentation factor, alpha subunit-like effector A
• ID: MGI:1270845

32 matching records from 32 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E3.5	E14.5	E15	E15.5	E16.5	E17	E17.5	E18	E18.5	E19.5	P
In situ RNA (section)			1					1			1
Immunohistochemistry (whole mount)	1
Northern blot									1		1
Western blot											1
RT-PCR		1		1	3	1	2	1	8	1	22

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cidea  cell death-inducing DNA fragmentation factor, alpha subunit-like effector A
Results	Reference
2	J:262187 Cautivo KM, Lizama CO, Tapia PJ, Agarwal AK, Garg A, Horton JD, Cortes VA, AGPAT2 is essential for postnatal development and maintenance of white and brown adipose tissue. Mol Metab. 2016 Jul;5(7):491-505
2	J:260351 Chen Q, Huang L, Pan D, Zhu LJ, Wang YX, Cbx4 Sumoylates Prdm16 to Regulate Adipose Tissue Thermogenesis. Cell Rep. 2018 Mar 13;22(11):2860-2872
3	J:324530 Fonseca TL, Russo SC, Luongo C, Salvatore D, Bianco AC, Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse. Endocrinology. 2022 May 1;163(5)
1	J:326089 Ghnaimawi S, Zhang S, Baum JI, Huang Y, The Effects of Maternal Intake of EPA and DHA Enriched Diet During Pregnancy and Lactation on Offspring's Muscle Development and Energy Homeostasis. Front Physiol. 2022;13:881624
3*	J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82
1	J:213153 Harms MJ, Ishibashi J, Wang W, Lim HW, Goyama S, Sato T, Kurokawa M, Won KJ, Seale P, Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice. Cell Metab. 2014 Apr 1;19(4):593-604
1*	J:314181 Holzman MA, Ryckman A, Finkelstein TM, Landry-Truchon K, Schindler KA, Bergmann JM, Jeannotte L, Mansfield JH, HOXA5 Participates in Brown Adipose Tissue and Epaxial Skeletal Muscle Patterning and in Brown Adipocyte Differentiation. Front Cell Dev Biol. 2021;9:632303
1	J:152000 Kajimura S, Seale P, Kubota K, Lunsford E, Frangioni JV, Gygi SP, Spiegelman BM, Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex. Nature. 2009 Aug 27;460(7259):1154-8
1	J:216177 Labialle S, Marty V, Bortolin-Cavaille ML, Hoareau-Osman M, Pradere JP, Valet P, Martin PG, Cavaille J, The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation. EMBO J. 2014 Oct 1;33(19):2216-30
1	J:294283 Liang Q, Zheng Q, Zuo Y, Chen Y, Ma J, Ni P, Cheng J, SENP2 Suppresses Necdin Expression to Promote Brown Adipocyte Differentiation. Cell Rep. 2019 Aug 20;28(8):2004-2011.e4
1	J:203690 Martinez-Lopez N, Athonvarangkul D, Sahu S, Coletto L, Zong H, Bastie CC, Pessin JE, Schwartz GJ, Singh R, Autophagy in Myf5+ progenitors regulates energy and glucose homeostasis through control of brown fat and skeletal muscle development. EMBO Rep. 2013 Sep;14(9):795-803
1	J:326530 Mau KHT, Karimlou D, Barneda D, Brochard V, Royer C, Leeke B, de Souza RA, Pailles M, Percharde M, Srinivas S, Jouneau A, Christian M, Azuara V, Dynamic enlargement and mobilization of lipid droplets in pluripotent cells coordinate morphogenesis during mouse peri-implantation development. Nat Commun. 2022 Jul 5;13(1):3861
3*	J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6
1*	J:96883 Olson LE, Zhang J, Taylor H, Rose DW, Rosenfeld MG, Barx2 functions through distinct corepressor classes to regulate hair follicle remodeling. Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3708-13
1	J:337469 Park A, Kim KE, Park I, Lee SH, Park KY, Jung M, Li X, Sleiman MB, Lee SJ, Kim DS, Kim J, Lim DS, Woo EJ, Lee EW, Han BS, Oh KJ, Lee SC, Auwerx J, Mun JY, Rhee HW, Kim WK, Bae KH, Suh JM, Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice. Nat Commun. 2023 Jun 23;14(1):3746
1	J:333724 Park EJ, Kim HS, Lee DH, Kim SM, Yoon JS, Lee JM, Im SJ, Lee H, Lee MW, Lee CW, Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation. Nat Commun. 2023 Feb 25;14(1):1097
1	J:198125 Rajakumari S, Wu J, Ishibashi J, Lim HW, Giang AH, Won KJ, Reed RR, Seale P, EBF2 determines and maintains brown adipocyte identity. Cell Metab. 2013 Apr 2;17(4):562-74
1*	J:273070 Rodriguez-de la Rosa L, Sanchez-Calderon H, Contreras J, Murillo-Cuesta S, Falagan S, Avendano C, Dopazo J, Varela-Nieto I, Milo M, Comparative gene expression study of the vestibular organ of the Igf1 deficient mouse using whole-transcript arrays. Hear Res. 2015 Dec;330(Pt A):62-77
1	J:270627 Sakakibara I, Wurmser M, Dos Santos M, Santolini M, Ducommun S, Davaze R, Guernec A, Sakamoto K, Maire P, Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle. Skelet Muscle. 2016;6(1):30
1	J:299569 Sanchez-Gurmaches J, Hung CM, Sparks CA, Tang Y, Li H, Guertin DA, PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors. Cell Metab. 2012 Sep 5;16(3):348-62
1	J:138823 Seale P, Bjork B, Yang W, Kajimura S, Chin S, Kuang S, Scime A, Devarakonda S, Conroe HM, Erdjument-Bromage H, Tempst P, Rudnicki MA, Beier DR, Spiegelman BM, PRDM16 controls a brown fat/skeletal muscle switch. Nature. 2008 Aug 21;454(7207):961-7
1	J:247178 Singh R, Braga M, Reddy ST, Lee SJ, Parveen M, Grijalva V, Vergnes L, Pervin S, Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues. Endocrinology. 2017 May 01;158(5):1217-1230
2	J:327433 Song Z, Xiaoli AM, Li Y, Siqin G, Wu T, Strich R, Pessin JE, Yang F, The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation. Mol Metab. 2022 Jul 19;64:101548
1	J:238410 Sun C, Berry WL, Olson LE, PDGFRalpha controls the balance of stromal and adipogenic cells during adipose tissue organogenesis. Development. 2017 Jan 01;144(1):83-94
2	J:232408 Van De Pette M, Tunster SJ, McNamara GI, Shelkovnikova T, Millership S, Benson L, Peirson S, Christian M, Vidal-Puig A, John RM, Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome. PLoS Genet. 2016 Mar;12(3):e1005916
2	J:269323 Vazquez P, Hernandez-Sanchez C, Escalona-Garrido C, Pereira L, Contreras C, Lopez M, Balsinde J, de Pablo F, Valverde AM, Increased FGF21 in brown adipose tissue of tyrosine hydroxylase heterozygous mice: implications for cold adaptation. J Lipid Res. 2018 Dec;59(12):2308-2320
1	J:168191 Yadav N, Cheng D, Richard S, Morel M, Iyer VR, Aldaz CM, Bedford MT, CARM1 promotes adipocyte differentiation by coactivating PPARgamma. EMBO Rep. 2008 Feb;9(2):193-8
1*	J:228546 Zhou H, Wan B, Grubisic I, Kaplan T, Tjian R, TAF7L modulates brown adipose tissue formation. Elife. 2014;3
5	J:85229 Zhou Z, Yon Toh S, Chen Z, Guo K, Ng CP, Ponniah S, Lin SC, Hong W, Li P, Cidea-deficient mice have lean phenotype and are resistant to obesity. Nat Genet. 2003 Sep;35(1):49-56
1	J:306153 Zhu M, Wang Q, Tian P, Cheng L, Sun Z, Hong Q, Lv P, Ji L, Liu Y, Tang QQ, Wen B, A long non-coding RNA specifically expressed in early embryos programs the metabolic balance in adult mice. Biochim Biophys Acta Mol Basis Dis. 2021 Jan 1;1867(1):165988
1	J:277057 Zhu X, Xie S, Xu T, Wu X, Han M, Rasal2 deficiency reduces adipogenesis and occurrence of obesity-related disorders. Mol Metab. 2017 Jun;6(6):494-502
1	J:262992 Zhuang L, Jang Y, Park YK, Lee JE, Jain S, Froimchuk E, Broun A, Liu C, Gavrilova O, Ge K, Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function. Nat Commun. 2018 May 4;9(1):1796