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Gene Expression Literature Summary
Symbol
Name
ID
Cdk8
cyclin dependent kinase 8
MGI:1196224

5 matching records from 5 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E2.5 E3 E3.5 E4.5 E5 E5.5 E9.5 E11.5 E14.5 P
Immunohistochemistry (section) 1 1 1 1 1 1 1 1 1
In situ reporter (knock in) 1
RT-PCR 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Cdk8  cyclin dependent kinase 8   (Synonyms: MGC:37111)
Results  Reference
1*J:45218 Ahuja HS, Zhu Y, Zakeri Z, Association of cyclin-dependent kinase 5 and its activator p35 with apoptotic cell death. Dev Genet. 1997;21(4):258-67
8J:307869 Lynch CJ, Bernad R, Martinez-Val A, Shahbazi MN, Nobrega-Pereira S, Calvo I, Blanco-Aparicio C, Tarantino C, Garreta E, Richart-Gines L, Alcazar N, Grana-Castro O, Gomez-Lopez G, Aksoy I, Munoz-Martin M, Martinez S, Ortega S, Prieto S, Simboeck E, Camasses A, Stephan-Otto Attolini C, Fernandez AF, Sierra MI, Fraga MF, Pastor J, Fisher D, Montserrat N, Savatier P, Munoz J, Zernicka-Goetz M, Serrano M, Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases. Nat Cell Biol. 2020 Oct;22(10):1223-1238
1J:304183 Ponce JM, Coen G, Spitler KM, Dragisic N, Martins I, Hinton A Jr, Mungai M, Tadinada SM, Zhang H, Oudit GY, Song LS, Li N, Sicinski P, Strack S, Abel ED, Mitchell C, Hall DD, Grueter CE, Stress-Induced Cyclin C Translocation Regulates Cardiac Mitochondrial Dynamics. J Am Heart Assoc. 2020 Apr 7;9(7):e014366
1*J:125327 Westerling T, Kuuluvainen E, Makela TP, Cdk8 is essential for preimplantation mouse development. Mol Cell Biol. 2007 Sep;27(17):6177-82
1J:187715 Xie L, Hoffmann AD, Burnicka-Turek O, Friedland-Little JM, Zhang K, Moskowitz IP, Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation. Dev Cell. 2012 Aug 14;23(2):280-91

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory