Gene Expression Literature Summary

• Symbol: Plcb4
• Name: phospholipase C, beta 4
• ID: MGI:107464

16 matching records from 16 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E9.5	E10.5	E11.5	E13.5	E14.5	E15.5	E17.5	E18	E18.5	P
Immunohistochemistry (section)								1		1	6
In situ RNA (section)				1	2	2	2			2	2
Immunohistochemistry (whole mount)									1		2
In situ RNA (whole mount)							1
In situ reporter (knock in)											1
RT-PCR	1	1	1								1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Plcb4  phospholipase C, beta 4   (Synonyms: A930039J07Rik, C230058B11Rik)
Results	Reference
1	J:170488 Blank MC, Grinberg I, Aryee E, Laliberte C, Chizhikov VV, Henkelman RM, Millen KJ, Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis. Development. 2011 Mar;138(6):1207-16
2	J:229091 Branco MR, King M, Perez-Garcia V, Bogutz AB, Caley M, Fineberg E, Lefebvre L, Cook SJ, Dean W, Hemberger M, Reik W, Maternal DNA Methylation Regulates Early Trophoblast Development. Dev Cell. 2016 Jan 25;36(2):152-63
1	J:245759 Casoni F, Croci L, Bosone C, D'Ambrosio R, Badaloni A, Gaudesi D, Barili V, Sarna JR, Tessarollo L, Cremona O, Hawkes R, Warming S, Consalez GG, Zfp423/ZNF423 regulates cell cycle progression, the mode of cell division and the DNA-damage response in Purkinje neuron progenitors. Development. 2017 Oct 15;144(20):3686-3697
1	J:317564 Filis P, Kind PC, Spears N, Implantation failure in mice with a disruption in Phospholipase C beta 1 gene: lack of embryonic attachment, aberrant steroid hormone signalling and defective endocannabinoid metabolism. Mol Hum Reprod. 2013 May;19(5):290-301
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1*	J:231595 Gurdziel K, Vogt KR, Walton KD, Schneider GK, Gumucio DL, Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun. Dev Dyn. 2016 May;245(5):614-26
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
3*	J:136999 Marzban H, Chung S, Watanabe M, Hawkes R, Phospholipase Cbeta4 expression reveals the continuity of cerebellar topography through development. J Comp Neurol. 2007 Jun 10;502(5):857-71
2	J:139387 Marzban H, Kim CT, Doorn D, Chung SH, Hawkes R, A novel transverse expression domain in the mouse cerebellum revealed by a neurofilament-associated antigen. Neuroscience. 2008 Jun 2;153(4):1190-201
1	J:302193 McDonough A, Elsen GE, Daza RM, Bachleda AR, Pizzo D, DelleTorri OM, Hevner RF, Unipolar (Dendritic) Brush Cells Are Morphologically Complex and Require Tbr2 for Differentiation and Migration. Front Neurosci. 2020;14:598548
1	J:251775 Miller KA, Tan TY, Welfare MF, White SM, Stark Z, Savarirayan R, Burgess T, Heggie AA, Caruana G, Bertram JF, Bateman JF, Farlie PG, A mouse splice-site mutant and individuals with atypical chromosome 22q11.2 deletions demonstrate the crucial role for crkl in craniofacial and pharyngeal development. Mol Syndromol. 2014 Dec;5(6):276-86
2	J:313455 Rahimi-Balaei M, Jiao X, Shabanipour S, Dixit R, Schuurmans C, Marzban H, Zebrin II Is Ectopically Expressed in Microglia in the Cerebellum of Neurogenin 2 Null Mice. Cerebellum. 2019 Feb;18(1):56-66
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
4	J:48405 Watanabe M, Nakamura M, Sato K, Kano M, Simon MI, Inoue Y, Patterns of expression for the mRNA corresponding to the four isoforms of phospholipase Cbeta in mouse brain. Eur J Neurosci. 1998 Jun;10(6):2016-25
1	J:293436 Wilson SL, Kalinovsky A, Orvis GD, Joyner AL, Spatially restricted and developmentally dynamic expression of engrailed genes in multiple cerebellar cell types. Cerebellum. 2011 Sep;10(3):356-72