Gene Expression Literature Summary

• Symbol: Hsd17b1
• Name: hydroxysteroid (17-beta) dehydrogenase 1
• ID: MGI:105077

15 matching records from 15 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E11	E12.5	E13.5	E14.5	E15	E15.5	E17	E	P
In situ RNA (section)					1				1	3
In situ reporter (knock in)										1
Northern blot	1	1				1		1	1	2
RT-PCR			2	3	2		3	1	1	6
cDNA clones										1
RNase protection										1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hsd17b1  hydroxysteroid (17-beta) dehydrogenase 1   (Synonyms: 17beta-HSD, Hsd17ba)
Results	Reference
2*	J:271281 Bowles J, Feng CW, Ineson J, Miles K, Spiller CM, Harley VR, Sinclair AH, Koopman P, Retinoic Acid Antagonizes Testis Development in Mice. Cell Rep. 2018 Jul 31;24(5):1330-1341
1	J:71679 Freiman RN, Albright SR, Zheng S, Sha WC, Hammer RE, Tjian R, Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development. Science. 2001 Sep 14;293(5537):2084-7
1	J:227517 Koizumi M, Oyama K, Yamakami Y, Kida T, Satoh R, Kato S, Hidema S, Oe T, Goto T, Clevers H, Nawa A, Nishimori K, Lgr4 controls specialization of female gonads in mice. Biol Reprod. 2015 Oct;93(4):90
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:143586 Manuylov NL, Smagulova FO, Leach L, Tevosian SG, Ovarian development in mice requires the GATA4-FOG2 transcription complex. Development. 2008 Nov;135(22):3731-43
2	J:44104 Mustonen M, Poutanen M, Chotteau-Lelievre A, de Launoit Y, Isomaa V, Vainio S, Vihko R, Vihko P, Ontogeny of 17beta-hydroxysteroid dehydrogenase type 2 mRNA expression in the developing mouse placenta and fetus. Mol Cell Endocrinol. 1997 Oct 31;134(1):33-40
5*	J:41672 Mustonen MVJ, Poutanen MH, Isomaa VV, Vihko PT, Vihko RK, Cloning of mouse 17beta-hydroxysteroid dehydrogenase type 2, and analysing expression of the mRNAs for types 1, 2, 3, 4 and 5 in mouse embryos and adult tissues. Biochem J. 1997 Jul 1;325(Pt 1):199-205
1	J:60196 Nokelainen P, Peltoketo H, Mustonen M, Vihko P, Expression of mouse 17beta-hydroxysteroid dehydrogenase/17-ketosteroid reductase type 7 in the ovary, uterus, and placenta: localization from implantation to late pregnancy. Endocrinology. 2000 Feb;141(2):772-8
5	J:32087 Nokelainen P, Puranen T, Peltoketo H, Orava M, Vihko P, Vihko R, Molecular cloning of mouse 17 beta-hydroxysteroid dehydrogenase type 1 and characterization of enzyme activity. Eur J Biochem. 1996 Mar 1;236(2):482-90
3*	J:33772 Sha J, Baker P, O'Shaughnessy PJ, Both reductive forms of 17 beta-hydroxysteroid dehydrogenase (types 1 and 3) are expressed during development in the mouse testis. Biochem Biophys Res Commun. 1996 May 6;222(1):90-4
2	J:133934 Tomizuka K, Horikoshi K, Kitada R, Sugawara Y, Iba Y, Kojima A, Yoshitome A, Yamawaki K, Amagai M, Inoue A, Oshima T, Kakitani M, R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling. Hum Mol Genet. 2008 May 1;17(9):1278-91
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
3	J:340792 Whiley PAF, Luu MCM, O'Donnell L, Handelsman DJ, Loveland KL, Testis exposure to unopposed/elevated activin A in utero affects somatic and germ cells and alters steroid levels mimicking phthalate exposure. Front Endocrinol (Lausanne). 2023;14:1234712
4	J:292644 Whiley PAF, O'Donnell L, Moody SC, Handelsman DJ, Young JC, Richards EA, Almstrup K, Western PS, Loveland KL, Activin A Determines Steroid Levels and Composition in the Fetal Testis. Endocrinology. 2020 Jul 1;161(7)
1*	J:220472 Zhao L, Svingen T, Ng ET, Koopman P, Female-to-male sex reversal in mice caused by transgenic overexpression of Dmrt1. Development. 2015 Mar 15;142(6):1083-8