Gene Expression Literature Summary

• Symbol: Myo6
• Name: myosin VI
• ID: MGI:104785

105 matching records from 105 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E10	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)		1	1	2	1	7	2	9	4	15	3	20	1	11	2	23	3	48
In situ RNA (section)								1								1		1
Immunohistochemistry (whole mount)								1		5		9		5	1	10		15
Western blot								1								1		2
RT-PCR	1		1		1	2	1	2	1	1	4	1		1	1	3		8
cDNA clones													1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Myo6  myosin VI   (Synonyms: Myo6, rsv, Tlc)
Results	Reference
2*	J:79317 Adato A, Vreugde S, Joensuu T, Avidan N, Hamalainen R, Belenkiy O, Olender T, Bonne-Tamir B, Ben-Asher E, Espinos C, Millan JM, Lehesjoki AE, Flannery JG, Avraham KB, Pietrokovski S, Sankila EM, Beckmann JS, Lancet D, USH3A transcripts encode clarin-1, a four-transmembrane-domain protein with a possible role in sensory synapses. Eur J Hum Genet. 2002 Jun;10(6):339-50
1	J:239394 Basch ML, Brown RM, Jen HI, Semerci F, Depreux F, Edlund RK, Zhang H, Norton CR, Gridley T, Cole SE, Doetzlhofer A, Maletic-Savatic M, Segil N, Groves AK, Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates. Elife. 2016 Dec 14;5:e19921
1	J:173382 Basch ML, Ohyama T, Segil N, Groves AK, Canonical Notch Signaling Is Not Necessary for Prosensory Induction in the Mouse Cochlea: Insights from a Conditional Mutant of RBPj{kappa}. J Neurosci. 2011 Jun 1;31(22):8046-58
2	J:226997 Bebee TW, Park JW, Sheridan KI, Warzecha CC, Cieply BW, Rohacek AM, Xing Y, Carstens RP, The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development. Elife. 2015;4
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
3	J:216617 Benito-Gonzalez A, Doetzlhofer A, Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signaling. J Neurosci. 2014 Sep 17;34(38):12865-76
2	J:55694 Bermingham NA, Hassan BA, Price SD, Vollrath MA, Ben-Arie N, Eatock RA, Bellen HJ, Lysakowski A, Zoghbi HY, Math1: an essential gene for the generation of inner ear hair cells. Science. 1999 Jun 11;284(5421):1837-41
3	J:337553 Bi Z, Li X, Ren M, Gu Y, Zhu T, Li S, Wang G, Sun S, Sun Y, Liu Z, Development and transdifferentiation into inner hair cells require Tbx2. Natl Sci Rev. 2022 Dec;9(12):nwac156
2	J:200759 Bok J, Zenczak C, Hwang CH, Wu DK, Auditory ganglion source of Sonic hedgehog regulates timing of cell cycle exit and differentiation of mammalian cochlear hair cells. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13869-74
1	J:154462 Breuskin I, Bodson M, Thelen N, Thiry M, Borgs L, Nguyen L, Lefebvre PP, Malgrange B, Sox10 promotes the survival of cochlear progenitors during the establishment of the organ of Corti. Dev Biol. 2009 Nov 15;335(2):327-39
1	J:164699 Breuskin I, Bodson M, Thelen N, Thiry M, Borgs L, Nguyen L, Stolt C, Wegner M, Lefebvre PP, Malgrange B, Glial but not neuronal development in the cochleo-vestibular ganglion requires Sox10. J Neurochem. 2010 Sep;114(6):1827-39
1	J:199162 Cai T, Seymour ML, Zhang H, Pereira FA, Groves AK, Conditional deletion of Atoh1 reveals distinct critical periods for survival and function of hair cells in the organ of Corti. J Neurosci. 2013 Jun 12;33(24):10110-22
2	J:332313 Cantu-Guerra HL, Papazian MR, Gorsky AL, Alekos NS, Caccavano A, Karagulyan N, Neef J, Vicini S, Moser T, Coate TM, Cochlear hair cell innervation is dependent on a modulatory function of Semaphorin-3A. Dev Dyn. 2023 Jan;252(1):124-144
1	J:137716 Chen Z, Montcouquiol M, Calderon R, Jenkins NA, Copeland NG, Kelley MW, Noben-Trauth K, Jxc1/Sobp, encoding a nuclear zinc finger protein, is critical for cochlear growth, cell fate, and patterning of the organ of corti. J Neurosci. 2008 Jun 25;28(26):6633-41
1	J:267727 Chessum L, Matern MS, Kelly MC, Johnson SL, Ogawa Y, Milon B, McMurray M, Driver EC, Parker A, Song Y, Codner G, Esapa CT, Prescott J, Trent G, Wells S, Dragich AK, Frolenkov GI, Kelley MW, Marcotti W, Brown SDM, Elkon R, Bowl MR, Hertzano R, Helios is a key transcriptional regulator of outer hair cell maturation. Nature. 2018 Nov;563(7733):696-700
1*	J:332881 Chiereghin C, Robusto M, Lewis MA, Caetano S, Massa V, Castorina P, Ambrosetti U, Steel KP, Duga S, Asselta R, Solda G, In-depth genetic and molecular characterization of diaphanous related formin 2 (DIAPH2) and its role in the inner ear. PLoS One. 2023;18(1):e0273586
4	J:226819 Coate TM, Spita NA, Zhang KD, Isgrig KT, Kelley MW, Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Elife. 2015;4
2	J:142229 Dabdoub A, Puligilla C, Jones JM, Fritzsch B, Cheah KS, Pevny LH, Kelley MW, Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18396-401
3	J:215675 Deng M, Luo XJ, Pan L, Yang H, Xie X, Liang G, Huang L, Hu F, Kiernan AE, Gan L, LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea. J Neurosci. 2014 Jul 23;34(30):10072-7
4*	J:83765 Donaudy F, Ferrara A, Esposito L, Hertzano R, Ben-David O, Bell RE, Melchionda S, Zelante L, Avraham KB, Gasparini P, Multiple Mutations of MYO1A, a Cochlear-Expressed Gene, in Sensorineural Hearing Loss. Am J Hum Genet. 2003 Jun;72(6):1571-7
2	J:139256 Driver EC, Pryor SP, Hill P, Turner J, Ruther U, Biesecker LG, Griffith AJ, Kelley MW, Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans. J Neurosci. 2008 Jul 16;28(29):7350-8
6*	J:195176 Driver EC, Sillers L, Coate TM, Rose MF, Kelley MW, The Atoh1-lineage gives rise to hair cells and supporting cells within the mammalian cochlea. Dev Biol. 2013 Apr 1;376(1):86-98
1*	J:330213 Ebeid M, Barnas K, Zhang H, Yaghmour A, Noreikaite G, Bjork BC, PRDM16 expression and function in mammalian cochlear development. Dev Dyn. 2022 Oct;251(10):1666-1683
1	J:201606 Ezan J, Lasvaux L, Gezer A, Novakovic A, May-Simera H, Belotti E, Lhoumeau AC, Birnbaumer L, Beer-Hammer S, Borg JP, Le Bivic A, Nurnberg B, Sans N, Montcouquiol M, Primary cilium migration depends on G-protein signalling control of subapical cytoskeleton. Nat Cell Biol. 2013 Sep;15(9):1107-15
1	J:148395 Friedman LM, Dror AA, Mor E, Tenne T, Toren G, Satoh T, Biesemeier DJ, Shomron N, Fekete DM, Hornstein E, Avraham KB, MicroRNAs are essential for development and function of inner ear hair cells in vertebrates. Proc Natl Acad Sci U S A. 2009 May 12;106(19):7915-20
1	J:161201 Gao N, Kaestner KH, Cdx2 regulates endo-lysosomal function and epithelial cell polarity. Genes Dev. 2010 Jun 15;24(12):1295-305
1	J:152162 Geller SF, Guerin KI, Visel M, Pham A, Lee ES, Dror AA, Avraham KB, Hayashi T, Ray CA, Reh TA, Bermingham-McDonogh O, Triffo WJ, Bao S, Isosomppi J, Vastinsalo H, Sankila EM, Flannery JG, CLRN1 is nonessential in the mouse retina but is required for cochlear hair cell development. PLoS Genet. 2009 Aug;5(8):e1000607
2	J:150215 Geng R, Geller SF, Hayashi T, Ray CA, Reh TA, Bermingham-McDonogh O, Jones SM, Wright CG, Melki S, Imanishi Y, Palczewski K, Alagramam KN, Flannery JG, Usher syndrome IIIA gene clarin-1 is essential for hair cell function and associated neural activation. Hum Mol Genet. 2009 Aug 1;18(15):2748-60
2	J:157099 Grimsley-Myers CM, Sipe CW, Geleoc GS, Lu X, The small GTPase Rac1 regulates auditory hair cell morphogenesis. J Neurosci. 2009 Dec 16;29(50):15859-69
1	J:180774 Grimsley-Myers CM, Sipe CW, Wu DK, Lu X, Redundant functions of Rac GTPases in inner ear morphogenesis. Dev Biol. 2012 Feb 15;362(2):172-86
2	J:231463 Haque K, Pandey AK, Zheng HW, Riazuddin S, Sha SH, Puligilla C, MEKK4 Signaling Regulates Sensory Cell Development and Function in the Mouse Inner Ear. J Neurosci. 2016 Jan 27;36(4):1347-61
2*	J:263979 Harley RJ, Murdy JP, Wang Z, Kelly MC, Ropp TF, Park SH, Maness PF, Manis PB, Coate TM, Neuronal cell adhesion molecule (NrCAM) is expressed by sensory cells in the cochlea and is necessary for proper cochlear innervation and sensory domain patterning during development. Dev Dyn. 2018 Mar 14;
3	J:266597 Hartman BH, Bscke R, Ellwanger DC, Keymeulen S, Scheibinger M, Heller S, Fbxo2(VHC) mouse and embryonic stem cell reporter lines delineate in vitro-generated inner ear sensory epithelia cells and enable otic lineage selection and Cre-recombination. Dev Biol. 2018 Nov 1;443(1):64-77
1	J:167107 Hartman BH, Nelson BR, Reh TA, Bermingham-McDonogh O, Delta/notch-like EGF-related receptor (DNER) is expressed in hair cells and neurons in the developing and adult mouse inner ear. J Assoc Res Otolaryngol. 2010 Jun;11(2):187-201
2	J:117235 Hayashi T, Cunningham D, Bermingham-McDonogh O, Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti. Dev Dyn. 2007 Feb;236(2):525-33
2*	J:135657 Hayashi T, Kokubo H, Hartman BH, Ray CA, Reh TA, Bermingham-McDonogh O, Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea. Dev Biol. 2008 Apr 1;316(1):87-99
2	J:137155 Hayashi T, Ray CA, Bermingham-McDonogh O, Fgf20 is required for sensory epithelial specification in the developing cochlea. J Neurosci. 2008 Jun 4;28(23):5991-9
2*	J:156926 Hayashi T, Ray CA, Younkins C, Bermingham-McDonogh O, Expression patterns of FGF receptors in the developing mammalian cochlea. Dev Dyn. 2010 Feb 3;239(3):1019-1026
3	J:119779 Hertzano R, Dror AA, Montcouquiol M, Ahmed ZM, Ellsworth B, Camper S, Friedman TB, Kelley MW, Avraham KB, Lhx3, a LIM domain transcription factor, is regulated by Pou4f3 in the auditory but not in the vestibular system. Eur J Neurosci. 2007 Feb;25(4):999-1005
7*	J:92833 Hertzano R, Montcouquiol M, Rashi-Elkeles S, Elkon R, Yucel R, Frankel WN, Rechavi G, Moroy T, Friedman TB, Kelley MW, Avraham KB, Transcription profiling of inner ears from Pou4f3(ddl/ddl) identifies Gfi1 as a target of the Pou4f3 deafness gene. Hum Mol Genet. 2004 Sep 15;13(18):2143-53
2	J:184501 Huh SH, Jones J, Warchol ME, Ornitz DM, Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal. PLoS Biol. 2012 Jan;10(1):e1001231
6*	J:123544 Hume CR, Bratt DL, Oesterle EC, Expression of LHX3 and SOX2 during mouse inner ear development. Gene Expr Patterns. 2007 Aug;7(7):798-807
2	J:315409 Huyghe A, Van den Ackerveken P, Sacheli R, Prevot PP, Thelen N, Renauld J, Thiry M, Delacroix L, Nguyen L, Malgrange B, MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5. Cell Rep. 2015 Oct 6;13(1):31-42
1	J:233511 Iizuka-Kogo A, Senda T, Akiyama T, Shimomura A, Nomura R, Hasegawa Y, Yamamura K, Kogo H, Sawai N, Matsuzaki T, Requirement of DLG1 for cardiovascular development and tissue elongation during cochlear, enteric, and skeletal development: possible role in convergent extension. PLoS One. 2015;10(4):e0123965
1	J:190885 Jacques BE, Puligilla C, Weichert RM, Ferrer-Vaquer A, Hadjantonakis AK, Kelley MW, Dabdoub A, A dual function for canonical Wnt/beta-catenin signaling in the developing mammalian cochlea. Development. 2012 Dec 1;139(23):4395-404
1	J:280423 Jansson L, Ebeid M, Shen JW, Mokhtari TE, Quiruz LA, Ornitz DM, Huh SH, Cheng AG, beta-Catenin is required for radial cell patterning and identity in the developing mouse cochlea. Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21054-21060
2	J:216288 Jones C, Qian D, Kim SM, Li S, Ren D, Knapp L, Sprinzak D, Avraham KB, Matsuzaki F, Chi F, Chen P, Ankrd6 is a mammalian functional homolog of Drosophila planar cell polarity gene diego and regulates coordinated cellular orientation in the mouse inner ear. Dev Biol. 2014 Nov 1;395(1):62-72
3	J:131308 Jones C, Roper VC, Foucher I, Qian D, Banizs B, Petit C, Yoder BK, Chen P, Ciliary proteins link basal body polarization to planar cell polarity regulation. Nat Genet. 2008 Jan;40(1):69-77
3	J:279215 Jung JS, Zhang KD, Wang Z, McMurray M, Tkaczuk A, Ogawa Y, Hertzano R, Coate TM, Semaphorin-5B Controls Spiral Ganglion Neuron Branch Refinement during Development. J Neurosci. 2019 Aug 14;39(33):6425-6438
5	J:336227 Karatsai O, Lehka L, Wojton D, Grabowska AI, Duda MK, Lenartowski R, Redowicz MJ, Unconventional myosin VI in the heart: Involvement in cardiac dysfunction progressing with age. Biochim Biophys Acta Mol Basis Dis. 2023 Aug;1869(6):166748
4	J:251343 Kim YJ, Wang SZ, Tymanskyj S, Ma L, Tao HW, Zhang LI, Dcc Mediates Functional Assembly of Peripheral Auditory Circuits. Sci Rep. 2016 Apr 4;6:23799
1	J:258238 Krey JF, Dumont RA, Wilmarth PA, David LL, Johnson KR, Barr-Gillespie PG, ELMOD1 Stimulates ARF6-GTP Hydrolysis to Stabilize Apical Structures in Developing Vestibular Hair Cells. J Neurosci. 2018 Jan 24;38(4):843-857
1	J:273200 Landin Malt A, Dailey Z, Holbrook-Rasmussen J, Zheng Y, Hogan A, Du Q, Lu X, Par3 is essential for the establishment of planar cell polarity of inner ear hair cells. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4999-5008
1	J:275301 Laos M, Sulg M, Herranen A, Anttonen T, Pirvola U, Indispensable role of Mdm2/p53 interaction during the embryonic and postnatal inner ear development. Sci Rep. 2017 Feb 9;7:42216
2	J:293995 Li C, Li X, Bi Z, Sugino K, Wang G, Zhu T, Liu Z, Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages. Elife. 2020 Jan 8;9:e50491
3	J:285042 Li C, Wang Y, Wang G, Lu Y, He S, Sun Y, Liu Z, Fate-mapping analysis using Rorb-IRES-Cre reveals apical-to-basal gradient of Rorb expression in mouse cochlea. Dev Dyn. 2020 Feb;249(2):173-186
7*	J:326361 Li S, Fan T, Li C, Wang Y, Li J, Liu Z, Fate-mapping analysis of cochlear cells expressing Atoh1 mRNA via a new Atoh1(3*HA-P2A-Cre) knockin mouse strain. Dev Dyn. 2022 Jul;251(7):1156-1174
3	J:336865 Li S, He S, Lu Y, Jia S, Liu Z, Epistatic genetic interactions between Insm1 and Ikzf2 during cochlear outer hair cell development. Cell Rep. 2023 May 30;42(5):112504
1	J:135642 Li S, Mark S, Radde-Gallwitz K, Schlisner R, Chin MT, Chen P, Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development. BMC Dev Biol. 2008;8:20
2*	J:238260 Liu TY, Chen YC, Jong YJ, Tsai HJ, Lee CC, Chang YS, Chang JG, Chang YF, Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice. Open Biol. 2017 Jan;7(1)
3	J:333396 Luo Z, Du Y, Li S, Zhang H, Shu M, Zhang D, He S, Wang G, Lu F, Liu Z, Three distinct Atoh1 enhancers cooperate for sound receptor hair cell development. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2119850119
1	J:219877 Lv K, Chen L, Li Y, Li Z, Zheng P, Liu Y, Chen J, Teng J, Trip6 promotes dendritic morphogenesis through dephosphorylated GRIP1-dependent myosin VI and F-actin organization. J Neurosci. 2015 Feb 11;35(6):2559-71
1*	J:190423 Macheda ML, Sun WW, Kugathasan K, Hogan BM, Bower NI, Halford MM, Zhang YF, Jacques BE, Lieschke GJ, Dabdoub A, Stacker SA, The Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling. J Biol Chem. 2012 Aug 24;287(35):29312-23
1	J:106101 Manji SS, Sorensen BS, Klockars T, Lam T, Hutchison W, Dahl HH, Molecular characterization and expression of maternally expressed gene 3 (Meg3/Gtl2) RNA in the mouse inner ear. J Neurosci Res. 2006 Feb 1;83(2):181-90
3	J:98518 Mantela J, Jiang Z, Ylikoski J, Fritzsch B, Zacksenhaus E, Pirvola U, The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear. Development. 2005 May;132(10):2377-88
2	J:91334 Mhatre AN, Li J, Kim Y, Coling DE, Lalwani AK, Cloning and developmental expression of nonmuscle myosin IIA (Myh9) in the mammalian inner ear. J Neurosci Res. 2004 May 1;76(3):296-305
2*	J:191199 Mulvaney JF, Yatteau A, Sun WW, Jacques B, Takubo K, Suda T, Yamada W, Dabdoub A, Secreted Factor R-Spondin 2 is Involved in Refinement of Patterning of the Mammalian Cochlea. Dev Dyn. 2013 Feb;242(2):179-88
1	J:279209 Murata J, Ohtsuka T, Tokunaga A, Nishiike S, Inohara H, Okano H, Kageyama R, Notch-Hes1 pathway contributes to the cochlear prosensory formation potentially through the transcriptional down-regulation of p27Kip1. J Neurosci Res. 2009 Dec;87(16):3521-34
3	J:305017 Nakano Y, Wiechert S, Fritzsch B, Banfi B, Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Dec;3(12)
1	J:166455 Ohyama T, Basch ML, Mishina Y, Lyons KM, Segil N, Groves AK, BMP signaling is necessary for patterning the sensory and nonsensory regions of the developing mammalian cochlea. J Neurosci. 2010 Nov 10;30(45):15044-51
1	J:201076 Okano T, Kelley MW, Expression of insulin-like growth factor binding proteins during mouse cochlear development. Dev Dyn. 2013 Oct;242(10):1210-21
4	J:178908 Okano T, Xuan S, Kelley MW, Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea. J Neurosci. 2011 Dec 7;31(49):18104-18
1	J:93155 Pirvola U, Zhang X, Mantela J, Ornitz DM, Ylikoski J, Fgf9 signaling regulates inner ear morphogenesis through epithelial-mesenchymal interactions. Dev Biol. 2004 Sep 15;273(2):350-60
1	J:340735 Rose KP, Manilla G, Milon B, Zalzman O, Song Y, Coate TM, Hertzano R, Spatially distinct otic mesenchyme cells show molecular and functional heterogeneity patterns before hearing onset. iScience. 2023 Oct 20;26(10):107769
2*	J:244196 Roux I, Wu JS, McIntosh JM, Glowatzki E, Assessment of the expression and role of the alpha1-nAChR subunit in efferent cholinergic function during the development of the mammalian cochlea. J Neurophysiol. 2016 Aug 01;116(2):479-92
1*	J:214438 Rudnicki A, Isakov O, Ushakov K, Shivatzki S, Weiss I, Friedman LM, Shomron N, Avraham KB, Next-generation sequencing of small RNAs from inner ear sensory epithelium identifies microRNAs and defines regulatory pathways. BMC Genomics. 2014;15:484
1*	J:210680 Rudnicki A, Shivatzki S, Beyer LA, Takada Y, Raphael Y, Avraham KB, microRNA-224 regulates Pentraxin 3, a component of the humoral arm of innate immunity, in inner ear inflammation. Hum Mol Genet. 2014 Jun 15;23(12):3138-46
3	J:286655 Sakamoto S, Tateya T, Omori K, Kageyama R, Id genes are required for morphogenesis and cellular patterning in the developing mammalian cochlea. Dev Biol. 2020 Apr 15;460(2):164-175
2	J:248731 Salehi P, Ge MX, Gundimeda U, Michelle Baum L, Lael Cantu H, Lavinsky J, Tao L, Myint A, Cruz C, Wang J, Nikolakopoulou AM, Abdala C, Kelley MW, Ohyama T, Coate TM, Friedman RA, Role of Neuropilin-1/Semaphorin-3A signaling in the functional and morphological integrity of the cochlea. PLoS Genet. 2017 Oct;13(10):e1007048
2	J:234621 Shibata S, Miwa T, Wu HH, Levitt P, Ohyama T, Hepatocyte Growth Factor-c-MET Signaling Mediates the Development of Nonsensory Structures of the Mammalian Cochlea and Hearing. J Neurosci. 2016 Aug 3;36(31):8200-9
2	J:195272 Sipe CW, Liu L, Lee J, Grimsley-Myers C, Lu X, Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization. Development. 2013 Apr;140(8):1785-95
1*	J:231461 Slowik AD, Bermingham-McDonogh O, A central to peripheral progression of cell cycle exit and hair cell differentiation in the developing mouse cristae. Dev Biol. 2016 Mar 1;411(1):1-14
1*	J:324832 Sun Y, Wang L, Zhu T, Wu B, Wang G, Luo Z, Li C, Wei W, Liu Z, Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages. Cell Rep. 2022 Mar 22;38(12):110542
2	J:308784 Tang Q, Xie MY, Zhang YL, Xue RY, Zhu XH, Yang H, Targeted deletion of Atoh8 results in severe hearing loss in mice. Genesis. 2021 Aug 17;:e23442
6*	J:297267 Tang Q, Xu M, Xu J, Xie X, Yang H, Gan L, Gfi1-GCE inducible Cre line for hair cell-specific gene manipulation in mouse inner ear. Genesis. 2019 Sep;57(9):e23304
1	J:105700 Tang W, Zhang Y, Chang Q, Ahmad S, Dahlke I, Yi H, Chen P, Paul DL, Lin X, Connexin29 is highly expressed in cochlear Schwann cells, and it is required for the normal development and function of the auditory nerve of mice. J Neurosci. 2006 Feb 15;26(7):1991-9
7	J:204446 Tateya T, Imayoshi I, Tateya I, Hamaguchi K, Torii H, Ito J, Kageyama R, Hedgehog signaling regulates prosensory cell properties during the basal-to-apical wave of hair cell differentiation in the mammalian cochlea. Development. 2013 Sep;140(18):3848-57
6	J:171468 Tateya T, Imayoshi I, Tateya I, Ito J, Kageyama R, Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development. Dev Biol. 2011 Apr 15;352(2):329-40
3	J:227032 Tateya T, Sakamoto S, Imayoshi I, Kageyama R, In vivo overactivation of the Notch signaling pathway in the developing cochlear epithelium. Hear Res. 2015 Sep;327:209-17
1*	J:336228 Thompson MJ, Young CA, Munnamalai V, Umulis DM, Early radial positional information in the cochlea is optimized by a precise linear BMP gradient and enhanced by SOX2. Sci Rep. 2023 May 26;13(1):8567
1*	J:237223 Torii H, Yoshida A, Katsuno T, Nakagawa T, Ito J, Omori K, Kinoshita M, Yamamoto N, Septin7 regulates inner ear formation at an early developmental stage. Dev Biol. 2016 Nov 15;419(2):217-228
1	J:221167 Urness LD, Wang X, Shibata S, Ohyama T, Mansour SL, Fgf10 is required for specification of non-sensory regions of the cochlear epithelium. Dev Biol. 2015 Apr 1;400(1):59-71
1	J:340444 Veithen M, Huyghe A, Van Den Ackerveken P, Fukada SI, Kokubo H, Breuskin I, Nguyen L, Delacroix L, Malgrange B, Sox9 Inhibits Cochlear Hair Cell Fate by Upregulating Hey1 and HeyL Antagonists of Atoh1. Cells. 2023 Aug 25;12(17)
4*	J:200791 Wakaoka T, Motohashi T, Hayashi H, Kuze B, Aoki M, Mizuta K, Kunisada T, Ito Y, Tracing Sox10-expressing cells elucidates the dynamic development of the mouse inner ear. Hear Res. 2013 Aug;302:17-25
3*	J:80025 Wallis D, Hamblen M, Zhou Y, Venken KJ, Schumacher A, Grimes HL, Zoghbi HY, Orkin SH, Bellen HJ, The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival. Development. 2003 Jan;130(1):221-32
2*	J:169193 Walsh T, Pierce SB, Lenz DR, Brownstein Z, Dagan-Rosenfeld O, Shahin H, Roeb W, McCarthy S, Nord AS, Gordon CR, Ben-Neriah Z, Sebat J, Kanaan M, Lee MK, Frydman M, King MC, Avraham KB, Genomic duplication and overexpression of TJP2/ZO-2 leads to altered expression of apoptosis genes in progressive nonsyndromic hearing loss DFNA51. Am J Hum Genet. 2010 Jul 9;87(1):101-9
1*	J:169194 Walsh T, Shahin H, Elkan-Miller T, Lee MK, Thornton AM, Roeb W, Abu Rayyan A, Loulus S, Avraham KB, King MC, Kanaan M, Whole exome sequencing and homozygosity mapping identify mutation in the cell polarity protein GPSM2 as the cause of nonsyndromic hearing loss DFNB82. Am J Hum Genet. 2010 Jul 9;87(1):90-4
3	J:199796 Wang SZ, Ibrahim LA, Kim YJ, Gibson DA, Leung HC, Yuan W, Zhang KK, Tao HW, Ma L, Zhang LI, Slit/Robo Signaling Mediates Spatial Positioning of Spiral Ganglion Neurons during Development of Cochlear Innervation. J Neurosci. 2013 Jul 24;33(30):12242-54
2	J:302429 Wang Z, Jung JS, Inbar TC, Rangoussis KM, Faaborg-Andersen C, Coate TM, The Purinergic Receptor P2rx3 is Required for Spiral Ganglion Neuron Branch Refinement during Development. eNeuro. 2020 Jul/Aug;7(4):ENEURO.0179-20.2020
7*	J:43752 Xiang M, Gao WQ, Hasson T, Shin JJ, Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells. Development. 1998 Oct;125(20):3935-46
3	J:173796 Yamamoto N, Chang W, Kelley MW, Rbpj regulates development of prosensory cells in the mammalian inner ear. Dev Biol. 2011 May 15;353(2):367-79
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