Gene Expression Literature Summary

• Symbol: Ddx3x
• Name: DEAD box helicase 3, X-linked
• ID: MGI:103064

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E1	E3	E3.5	E4	E6.5	E7.5	E8.5	E9	E9.5	E10.5	E11.5	E12.5	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17.5	E18.5	E	P
Immunohistochemistry (section)					1	1	1		1						2				1				2
In situ RNA (section)								1			1	2	1	1	3		1		2		1		5
Immunohistochemistry (whole mount)	1
In situ RNA (whole mount)	1
Northern blot										1	2		2				1						4
Western blot													1		2								2
RT-PCR		2	1	1	1		1		3	2	2	1	1			1	1	1		1		2	8
cDNA clones							1		1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ddx3x  DEAD box helicase 3, X-linked   (Synonyms: D1Pas1-rs2, Ddx3, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked, embryonic RNA helicase, Fin14)
Results	Reference
2	J:100324 Bulfone A, Carotenuto P, Faedo A, Aglio V, Garzia L, Bello AM, Basile A, Andre A, Cocchia M, Guardiola O, Ballabio A, Rubenstein JL, Zollo M, Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes. J Neurosci. 2005 Aug 17;25(33):7586-600
12	J:231798 Chen CY, Chan CH, Chen CM, Tsai YS, Tsai TY, Wu Lee YH, You LR, Targeted inactivation of murine Ddx3x: essential roles of Ddx3x in placentation and embryogenesis. Hum Mol Genet. 2016 July 15;25(14):2905-2922
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
5*	J:32076 Guthridge MA, Seldin M, Basilico C, Induction of expression of growth-related genes by FGF-4 in mouse fibroblasts. Oncogene. 1996 Mar 21;12(6):1267-78
1	J:282329 Hildebrandt MR, Wang Y, Li L, Yasmin L, Glubrecht DD, Godbout R, Cytoplasmic aggregation of DDX1 in developing embryos: Early embryonic lethality associated with Ddx1 knockout. Dev Biol. 2019 Nov 15;455(2):420-433
3	J:326220 Hoye ML, Calviello L, Poff AJ, Ejimogu NE, Newman CR, Montgomery MD, Ou J, Floor SN, Silver DL, Aberrant cortical development is driven by impaired cell cycle and translational control in a DDX3X syndrome model. Elife. 2022 Jun 28;11:e78203
2	J:150959 Kalantry S, Purushothaman S, Bowen RB, Starmer J, Magnuson T, Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation. Nature. 2009 Jul 30;460(7255):647-51
1	J:329968 Kazi S, Castaneda JM, Savolainen A, Xu Y, Liu N, Qiao H, Ramirez-Solis R, Nozawa K, Yu Z, Matzuk MM, Prunskaite-Hyyrylainen R, MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice. FASEB J. 2022 Sep;36(9):e22479
3	J:223034 Krol J, Krol I, Alvarez CP, Fiscella M, Hierlemann A, Roska B, Filipowicz W, A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture. Nat Commun. 2015;6:7305
7	J:292736 Lennox AL, Hoye ML, Jiang R, Johnson-Kerner BL, Suit LA, Venkataramanan S, Sheehan CJ, Alsina FC, Fregeau B, Aldinger KA, Moey C, Lobach I, Afenjar A, Babovic-Vuksanovic D, Bezieau S, Blackburn PR, Bunt J, Burglen L, Campeau PM, Charles P, Chung BHY, Cogne B, Curry C, D'Agostino MD, Di Donato N, Faivre L, Heron D, Innes AM, Isidor B, Keren B, Kimball A, Klee EW, Kuentz P, Kury S, Martin-Coignard D, Mirzaa G, Mignot C, Miyake N, Matsumoto N, Fujita A, Nava C, Nizon M, Rodriguez D, Blok LS, Thauvin-Robinet C, Thevenon J, Vincent M, Ziegler A, Dobyns W, Richards LJ, Barkovich AJ, Floor SN, Silver DL, Sherr EH, Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development. Neuron. 2020 May 6;106(3):404-420.e8
1	J:185555 Mugford JW, Yee D, Magnuson T, Failure of extra-embryonic progenitor maintenance in the absence of dosage compensation. Development. 2012 Jun;139(12):2130-8
1	J:186666 Pang CJ, Lemsaddek W, Alhashem YN, Bondzi C, Redmond LC, Ah-Son N, Dumur CI, Archer KJ, Haar JL, Lloyd JA, Trudel M, Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis. Mol Cell Biol. 2012 Jul;32(13):2628-44
2	J:296045 Patmore DM, Jassim A, Nathan E, Gilbertson RJ, Tahan D, Hoffmann N, Tong Y, Smith KS, Kanneganti TD, Suzuki H, Taylor MD, Northcott P, Gilbertson RJ, DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma. Dev Cell. 2020 Aug 24;54(4):455-470.e5
11*	J:26244 Sowden J, Putt W, Morrison K, Beddington R, Edwards Y, The embryonic RNA helicase gene (ERH): a new member of the DEAD box family of RNA helicases. Biochem J. 1995 Jun 15;308(Pt 3):839-46
5*	J:38063 Sowden JC, Morrison K, Putt W, Beddington R, Edwards YH, The identification of novel sequences expressed in the mouse notochord. Mamm Genome. 1997 Jan;8(1):42-4
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
7*	J:110867 Vong QP, Li Y, Lau YF, Dym M, Rennert OM, Chan WY, Structural characterization and expression studies of dby and its homologs in the mouse. J Androl. 2006 Sep-Oct;27(5):653-61
1	J:346696 Wei C, Kesner B, Yin H, Lee JT, Imprinted X chromosome inactivation at the gamete-to-embryo transition. Mol Cell. 2024 Feb 29;
3	J:171449 Williams LH, Kalantry S, Starmer J, Magnuson T, Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass. Development. 2011 May;138(10):2049-57
4*	J:76911 Xu J, Burgoyne PS, Arnold AP, Sex differences in sex chromosome gene expression in mouse brain. Hum Mol Genet. 2002 Jun 1;11(12):1409-19