Gene Expression Literature Summary

• Symbol: Lhx3
• Name: LIM homeobox protein 3
• ID: MGI:102673

198 matching records from 198 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19	E20	E	P
Immunohistochemistry (section)			1	6	10	43	2	44	3	54	1	36	1	12	1	4	1	3	1	2		7			5	8
In situ RNA (section)	1	1		13	1	17	1	13	1	12	2	14	1	5	1	14	2	2	1	5	1	1	1	1	2	14
Immunohistochemistry (whole mount)										1
In situ RNA (whole mount)	1	2	1	2		2		2								1	1									1
In situ reporter (knock in)												1		1		1		1		1						1
Northern blot								1													1		1	1		2
Western blot								1
RT-PCR				2		1		4	1	1		2		1		3	1	2		2		1			1	5
cDNA clones							1	1																		1
RNase protection																										1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Lhx3  LIM homeobox protein 3   (Synonyms: Lim3, mLim-3, P-LIM)
Results	Reference
2	J:172398 Ackermann J, Ashton G, Lyons S, James D, Hornung JP, Jones N, Breitwieser W, Loss of ATF2 Function Leads to Cranial Motoneuron Degeneration during Embryonic Mouse Development. PLoS One. 2011;6(4):e19090
1	J:222718 Adams KL, Rousso DL, Umbach JA, Novitch BG, Foxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells. Nat Commun. 2015;6:6778
1	J:155074 Agalliu D, Takada S, Agalliu I, McMahon AP, Jessell TM, Motor neurons with axial muscle projections specified by Wnt4/5 signaling. Neuron. 2009 Mar 12;61(5):708-20
2*	J:104158 Alanentalo T, Chatonnet F, Karlen M, Sulniute R, Ericson J, Andersson E, Ahlgren U, Cloning and analysis of Nkx6.3 during CNS and gastrointestinal development. Gene Expr Patterns. 2006 Jan;6(2):162-70
1	J:227113 Amin ND, Bai G, Klug JR, Bonanomi D, Pankratz MT, Gifford WD, Hinckley CA, Sternfeld MJ, Driscoll SP, Dominguez B, Lee KF, Jin X, Pfaff SL, Loss of motoneuron-specific microRNA-218 causes systemic neuromuscular failure. Science. 2015 Dec 18;350(6267):1525-9
6	J:57340 Arber S, Han B, Mendelsohn M, Smith M, Jessell TM, Sockanathan S, Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity. Neuron. 1999 Aug;23(4):659-74
1	J:223814 Aujla PK, Bogdanovic V, Naratadam GT, Raetzman LT, Persistent expression of activated notch in the developing hypothalamus affects survival of pituitary progenitors and alters pituitary structure. Dev Dyn. 2015 Aug;244(8):921-34
4	J:41049 Bach I, Carriere C, Ostendorff HP, Andersen B, Rosenfeld MG, A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins. Genes Dev. 1997 Jun 1;11(11):1370-80
4*	J:24155 Bach I, Rhodes SJ, Pearse RV 2nd, Heinzel T, Gloss B, Scully KM, Sawchenko PE, Rosenfeld MG, P-Lim, a LIM homeodomain factor, is expressed during pituitary organ and cell commitment and synergizes with Pit-1. Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):2720-4
1	J:257081 Bai G, Chivatakarn O, Bonanomi D, Lettieri K, Franco L, Xia C, Stein E, Ma L, Lewcock JW, Pfaff SL, Presenilin-dependent receptor processing is required for axon guidance. Cell. 2011 Jan 7;144(1):106-18
1*	J:207154 Balasubramanian R, Bui A, Ding Q, Gan L, Expression of LIM-homeodomain transcription factors in the developing and mature mouse retina. Gene Expr Patterns. 2014 Jan;14(1):1-8
3	J:334460 Bando H, Brinkmeier ML, Castinetti F, Fang Q, Lee MS, Saveanu A, Albarel F, Dupuis C, Brue T, Camper SA, Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man. Hum Mol Genet. 2023 Jan 13;32(3):367-385
4	J:169150 Bharti K, Gasper M, Bertuzzi S, Arnheiter H, Lack of the ventral anterior homeodomain transcription factor VAX1 leads to induction of a second pituitary. Development. 2011 Mar;138(5):873-8
3*	J:290740 Brachet C, Kozhemyakina EA, Boros E, Heinrichs C, Balikova I, Soblet J, Smits G, Vilain C, Mathers PH, Truncating RAX Mutations: Anophthalmia, Hypopituitarism, Diabetes Insipidus, and Cleft Palate in Mice and Men. J Clin Endocrinol Metab. 2019 Jul 1;104(7):2925-2930
1	J:309359 Brinkmeier ML, Bando H, Camarano AC, Fujio S, Yoshimoto K, de Souza FS, Camper SA, Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors. J Clin Invest. 2020 Aug 3;130(8):4501-4515
1	J:127546 Brinkmeier ML, Potok MA, Davis SW, Camper SA, TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors. Dev Biol. 2007 Nov 15;311(2):396-407
1	J:54240 Briscoe J, Sussel L, Serup P, Hartigan-O'Connor D, Jessell TM , Rubenstein JL , Ericson J, Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling. Nature. 1999 Apr 15;398(6728):622-7
1	J:217405 Carcagno AL, Di Bella DJ, Goulding M, Guillemot F, Lanuza GM, Neurogenin3 restricts serotonergic neuron differentiation to the hindbrain. J Neurosci. 2014 Nov 12;34(46):15223-33
5	J:245758 Carreno G, Apps JR, Lodge EJ, Panousopoulos L, Haston S, Gonzalez-Meljem JM, Hahn H, Andoniadou CL, Martinez-Barbera JP, Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors. Development. 2017 Sep 15;144(18):3289-3302
1	J:120712 Caspary T, Larkins CE, Anderson KV, The graded response to sonic hedgehog depends on cilia architecture. Dev Cell. 2007 May;12(5):767-78
2	J:322321 Catela C, Chen Y, Weng Y, Wen K, Kratsios P, Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity. Elife. 2022 Mar 22;11:e70766
5	J:272505 Catela C, Correa E, Wen K, Aburas J, Croci L, Consalez GG, Kratsios P, An ancient role for collier/Olf/Ebf (COE)-type transcription factors in axial motor neuron development. Neural Dev. 2019 Jan 18;14(1):2
1	J:95393 Cepeda-Nieto AC, Pfaff SL, Varela-Echavarria A, Homeodomain transcription factors in the development of subsets of hindbrain reticulospinal neurons. Mol Cell Neurosci. 2005 Jan;28(1):30-41
1*	J:90448 Cha KB, Douglas KR, Potok MA, Liang H, Jones SN, Camper SA, WNT5A signaling affects pituitary gland shape. Mech Dev. 2004 Feb;121(2):183-94
1	J:284139 Chaimowicz C, Ruffault PL, Cheret C, Woehler A, Zampieri N, Fortin G, Garratt AN, Birchmeier C, Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse. Development. 2019 Sep 6;146(17):dev174045
2	J:304721 Chang SH, Su YC, Chang M, Chen JA, MicroRNAs mediate precise control of spinal interneuron populations to exert delicate sensory-to-motor outputs. Elife. 2021 Mar 31;10:e63768
1	J:99227 Charles MA, Suh H, Hjalt TA, Drouin J, Camper SA, Gage PJ, PITX genes are required for cell survival and Lhx3 activation. Mol Endocrinol. 2005 Jul;19(7):1893-903
1	J:174745 Chen JA, Huang YP, Mazzoni EO, Tan GC, Zavadil J, Wichterle H, Mir-17-3p controls spinal neural progenitor patterning by regulating Olig2/Irx3 cross-repressive loop. Neuron. 2011 Feb 24;69(4):721-35
1	J:190166 Chen JA, Wichterle H, Apoptosis of limb innervating motor neurons and erosion of motor pool identity upon lineage specific dicer inactivation. Front Neurosci. 2012;6:69
1	J:266104 Choi JH, Jo HS, Lim S, Kim HT, Lee KW, Moon KH, Ha T, Kwak SS, Kim Y, Lee EJ, Joe CO, Kim JW, mTORC1 accelerates retinal development via the immunoproteasome. Nat Commun. 2018 Jun 27;9(1):2502
1	J:109407 Chou SJ, Hermesz E, Hatta T, Feltner D, El-Hodiri HM, Jamrich M, Mahon K, Conserved regulatory elements establish the dynamic expression of Rpx/HesxI in early vertebrate development. Dev Biol. 2006 Apr 15;292(2):533-45
2*	J:168654 Chung YC, Tsai YJ, Shiu TY, Sun YY, Wang PF, Chen CL, Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):84-92
1	J:238975 Clovis YM, Seo SY, Kwon JS, Rhee JC, Yeo S, Lee JW, Lee S, Lee SK, Chx10 Consolidates V2a Interneuron Identity through Two Distinct Gene Repression Modes. Cell Rep. 2016 Aug 09;16(6):1642-52
1	J:306254 Crane-Smith Z, Schoenebeck J, Graham KA, Devenney PS, Rose L, Ditzell M, Anderson E, Thomson JI, Klenin N, Kurrasch DM, Lettice LA, Hill RE, A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development. Front Cell Dev Biol. 2021;9:595744
4*	J:73085 Dasen JS, Barbera JP, Herman TS, Connell SO, Olson L, Ju B, Tollkuhn J, Baek SH, Rose DW, Rosenfeld MG, Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 2001 Dec 1;15(23):3193-207
4	J:139297 Dasen JS, De Camilli A, Wang B, Tucker PW, Jessell TM, Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1. Cell. 2008 Jul 25;134(2):304-16
2*	J:121318 Davis SW, Camper SA, Noggin regulates Bmp4 activity during pituitary induction. Dev Biol. 2007 May 1;305(1):145-60
2	J:235514 Davis SW, Mortensen AH, Keisler JL, Zacharias AL, Gage PJ, Yamamura K, Camper SA, beta-catenin is required in the neural crest and mesencephalon for pituitary gland organogenesis. BMC Dev Biol. 2016;16(1):16
1	J:132705 De Marco Garcia NV, Jessell TM, Early motor neuron pool identity and muscle nerve trajectory defined by postmitotic restrictions in Nkx6.1 activity. Neuron. 2008 Jan 24;57(2):217-31
2	J:299679 Debrulle S, Baudouin C, Hidalgo-Figueroa M, Pelosi B, Francius C, Rucchin V, Ronellenfitch K, Chow RL, Tissir F, Lee SK, Clotman F, Vsx1 and Chx10 paralogs sequentially secure V2 interneuron identity during spinal cord development. Cell Mol Life Sci. 2020 Oct;77(20):4117-4131
1	J:128001 Del Barrio MG, Taveira-Marques R, Muroyama Y, Yuk DI, Li S, Wines-Samuelson M, Shen J, Smith HK, Xiang M, Rowitch D, Richardson WD, A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor pool. Development. 2007 Oct;134(19):3427-36
2	J:178688 Demireva EY, Shapiro LS, Jessell TM, Zampieri N, Motor neuron position and topographic order imposed by beta- and gamma-catenin activities. Cell. 2011 Oct 28;147(3):641-52
1	J:283226 Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, Fletcher EV, Vanwelden T, Schmidt BZ, Henningfeld KA, Pieler T, Woods CG, Nagy V, Verfaillie C, Bellefroid EJ, Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA. Cell Rep. 2019 Mar 26;26(13):3522-3536.e5
1	J:271772 Dewitz C, Pimpinella S, Hackel P, Akalin A, Jessell TM, Zampieri N, Nuclear Organization in the Spinal Cord Depends on Motor Neuron Lamination Orchestrated by Catenin and Afadin Function. Cell Rep. 2018 Feb 13;22(7):1681-1694
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:40032 Dou C, Ye X, Stewart C, Lai E, Li SC, TWH regulates the development of subsets of spinal cord neurons. Neuron. 1997 Apr;18(4):539-51
1	J:209344 Dougherty KJ, Zagoraiou L, Satoh D, Rozani I, Doobar S, Arber S, Jessell TM, Kiehn O, Locomotor rhythm generation linked to the output of spinal shox2 excitatory interneurons. Neuron. 2013 Nov 20;80(4):920-33
2	J:262472 Edmond M, Hanley O, Philippidou P, Topoisomerase IIbeta Selectively Regulates Motor Neuron Identity and Peripheral Connectivity through Hox/Pbx-Dependent Transcriptional Programs. eNeuro. 2017 Nov-Dec;4(6):ENEURO.0404-17.2017
1*	J:70423 Eggenschwiler JT, Espinoza E, Anderson KV, Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway. Nature. 2001 Jul 12;412(6843):194-8
6*	J:46975 Ericson J, Norlin S, Jessell TM, Edlund T, Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary. Development. 1998 Mar;125(6):1005-15
3	J:41620 Ericson J, Rashbass P, Schedl A, Brenner-Morton S, Kawakami A , van Heyningen V , Jessell TM , Briscoe J, Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling. Cell. 1997 Jul 11;90(1):169-80
7	J:158231 Francius C, Clotman F, Dynamic expression of the Onecut transcription factors HNF-6, OC-2 and OC-3 during spinal motor neuron development. Neuroscience. 2010 Jan 13;165(1):116-29
1	J:240621 Francius C, Hidalgo-Figueroa M, Debrulle S, Pelosi B, Rucchin V, Ronellenfitch K, Panayiotou E, Makrides N, Misra K, Harris A, Hassani H, Schakman O, Parras C, Xiang M, Malas S, Chow RL, Clotman F, Vsx1 Transiently Defines an Early Intermediate V2 Interneuron Precursor Compartment in the Mouse Developing Spinal Cord. Front Mol Neurosci. 2016;9:145
1*	J:51160 Gage PJ, Suh H, Camper SA, Dosage requirement of Pitx2 for development of multiple organs. Development. 1999 Oct;126(20):4643-51
1	J:312043 Galdo M, Gregonis J, Fiore CS, Compagnone NA, Dehydroepiandrosterone biosynthesis, role, and mechanism of action in the developing neural tube. Front Endocrinol (Lausanne). 2012;3:16
2	J:174144 Gaston-Massuet C, Andoniadou CL, Signore M, Jayakody SA, Charolidi N, Kyeyune R, Vernay B, Jacques TS, Taketo MM, Le Tissier P, Dattani MT, Martinez-Barbera JP, From the Cover: Increased Wingless (Wnt) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans. Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11482-7
3	J:142425 Gaston-Massuet C, Andoniadou CL, Signore M, Sajedi E, Bird S, Turner JM, Martinez-Barbera JP, Genetic interaction between the homeobox transcription factors HESX1 and SIX3 is required for normal pituitary development. Dev Biol. 2008 Dec 15;324(2):322-33
3	J:229902 Gaston-Massuet C, McCabe MJ, Scagliotti V, Young RM, Carreno G, Gregory LC, Jayakody SA, Pozzi S, Gualtieri A, Basu B, Koniordou M, Wu CI, Bancalari RE, Rahikkala E, Veijola R, Lopponen T, Graziola F, Turton J, Signore M, Mousavy Gharavy SN, Charolidi N, Sokol SY, Andoniadou CL, Wilson SW, Merrill BJ, Dattani MT, Martinez-Barbera JP, Transcription factor 7-like 1 is involved in hypothalamo-pituitary axis development in mice and humans. Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E548-57
6	J:231503 Gergics P, Brinkmeier ML, Camper SA, Lhx4 deficiency: increased cyclin-dependent kinase inhibitor expression and pituitary hypoplasia. Mol Endocrinol. 2015 Apr;29(4):597-612
2	J:235668 Goldsmith S, Lovell-Badge R, Rizzoti K, SOX2 is sequentially required for progenitor proliferation and lineage specification in the developing pituitary. Development. 2016 Jul 1;143(13):2376-88
2	J:333567 Gonzalez-Meljem JM, Ivins S, Andoniadou CL, Le Tissier P, Scambler P, Martinez-Barbera JP, An expression and function analysis of the CXCR4/SDF-1 signalling axis during pituitary gland development. PLoS One. 2023;18(2):e0280001
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1*	J:229257 Gu Z, Imai F, Kim IJ, Fujita H, Katayama Ki, Mori K, Yoshihara Y, Yoshida Y, Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550
2	J:305202 Gualtieri A, Kyprianou N, Gregory LC, Vignola ML, Nicholson JG, Tan R, Inoue SI, Scagliotti V, Casado P, Blackburn J, Abollo-Jimenez F, Marinelli E, Besser REJ, Hogler W, Karen Temple I, Davies JH, Gagunashvili A, Robinson ICAF, Camper SA, Davis SW, Cutillas PR, Gevers EF, Aoki Y, Dattani MT, Gaston-Massuet C, Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans. Nat Commun. 2021 Apr 1;12(1):2028
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:117093 Gui H, Li S, Matise MP, A cell-autonomous requirement for Cip/Kip cyclin-kinase inhibitors in regulating neuronal cell cycle exit but not differentiation in the developing spinal cord. Dev Biol. 2007 Jan 1;301(1):14-26
6	J:195620 Gumbel JH, Patterson EM, Owusu SA, Kabat BE, Jung DO, Simmons J, Hopkins T, Ellsworth BS, The forkhead transcription factor, Foxd1, is necessary for pituitary luteinizing hormone expression in mice. PLoS One. 2012;7(12):e52156
2*	J:139734 Hafler BP, Choi MY, Shivdasani RA, Rowitch DH, Expression and function of Nkx6.3 in vertebrate hindbrain. Brain Res. 2008 Jul 30;1222:42-50
4	J:253351 Hanley O, Zewdu R, Cohen LJ, Jung H, Lacombe J, Philippidou P, Lee DH, Selleri L, Dasen JS, Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns. Neuron. 2016 Sep 7;91(5):1005-1020
1*	J:60974 Hargrave M, Karunaratne A, Cox L, Wood S, Koopman P, Yamada T, The HMG box transcription factor gene Sox14 marks a novel subset of ventral interneurons and is regulated by sonic hedgehog. Dev Biol. 2000 Mar 1;219(1):142-53
13	J:119779 Hertzano R, Dror AA, Montcouquiol M, Ahmed ZM, Ellsworth B, Camper S, Friedman TB, Kelley MW, Avraham KB, Lhx3, a LIM domain transcription factor, is regulated by Pou4f3 in the auditory but not in the vestibular system. Eur J Neurosci. 2007 Feb;25(4):999-1005
1*	J:177585 Hesse K, Vaupel K, Kurt S, Buettner R, Kirfel J, Moser M, AP-2delta is a crucial transcriptional regulator of the posterior midbrain. PLoS One. 2011;6(8):e23483
1*	J:174196 Heydeck W, Liu A, PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube. Dev Dyn. 2011 Aug;240(8):1938-48
2*	J:143548 Himes AD, Raetzman LT, Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1. Dev Biol. 2009 Jan 1;325(1):151-61
1	J:255024 Hinckley CA, Alaynick WA, Gallarda BW, Hayashi M, Hilde KL, Driscoll SP, Dekker JD, Tucker HO, Sharpee TO, Pfaff SL, Spinal Locomotor Circuits Develop Using Hierarchical Rules Based on Motorneuron Position and Identity. Neuron. 2015 Sep 2;87(5):1008-21
1	J:166771 Holz A, Kollmus H, Ryge J, Niederkofler V, Dias J, Ericson J, Stoeckli ET, Kiehn O, Arnold HH, The transcription factors Nkx2.2 and Nkx2.9 play a novel role in floor plate development and commissural axon guidance. Development. 2010 Dec;137(24):4249-60
1	J:142506 Hoover AN, Wynkoop A, Zeng H, Jia J, Niswander LA, Liu A, C2cd3 is required for cilia formation and Hedgehog signaling in mouse. Development. 2008 Dec;135(24):4049-58
2	J:345795 Hsu HC, Hsu SP, Hsu FY, Chang M, Chen JA, LncRNA Litchi is a regulator for harmonizing maturity and resilient functionality in spinal motor neurons. iScience. 2024 Mar 15;27(3):109207
1	J:100466 Huangfu D, Anderson KV, Cilia and Hedgehog responsiveness in the mouse. Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11325-30
1	J:107594 Huber AB, Kania A, Tran TS, Gu C, De Marco Garcia N, Lieberam I, Johnson D, Jessell TM, Ginty DD, Kolodkin AL, Distinct roles for secreted semaphorin signaling in spinal motor axon guidance. Neuron. 2005 Dec 22;48(6):949-64
1	J:231979 Huettl RE, Eckstein S, Stahl T, Petricca S, Ninkovic J, Gotz M, Huber AB, Functional dissection of the Pax6 paired domain: Roles in neural tube patterning and peripheral nervous system development. Dev Biol. 2016 May 1;413(1):86-103
6*	J:123544 Hume CR, Bratt DL, Oesterle EC, Expression of LHX3 and SOX2 during mouse inner ear development. Gene Expr Patterns. 2007 Aug;7(7):798-807
1	J:208600 Hunter CS, Dixit S, Cohen T, Ediger B, Wilcox C, Ferreira M, Westphal H, Stein R, May CL, Islet alpha-, beta-, and delta-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor. Diabetes. 2013 Mar;62(3):875-86
2	J:191667 Jayakody SA, Andoniadou CL, Gaston-Massuet C, Signore M, Cariboni A, Bouloux PM, Le Tissier P, Pevny LH, Dattani MT, Martinez-Barbera JP, SOX2 regulates the hypothalamic-pituitary axis at multiple levels. J Clin Invest. 2012 Oct 1;122(10):3635-46
2	J:112635 Ji SJ, Zhuang B, Falco C, Schneider A, Schuster-Gossler K, Gossler A, Sockanathan S, Mesodermal and neuronal retinoids regulate the induction and maintenance of limb innervating spinal motor neurons. Dev Biol. 2006 Sep 1;297(1):249-61
2	J:166088 Jung H, Lacombe J, Mazzoni EO, Liem KF Jr, Grinstein J, Mahony S, Mukhopadhyay D, Gifford DK, Young RA, Anderson KV, Wichterle H, Dasen JS, Global control of motor neuron topography mediated by the repressive actions of a single hox gene. Neuron. 2010 Sep 9;67(5):781-96
1	J:186538 Katayama K, Leslie JR, Lang RA, Zheng Y, Yoshida Y, Left-Right Locomotor Circuitry Depends on RhoA-Driven Organization of the Neuroepithelium in the Developing Spinal Cord. J Neurosci. 2012 Jul 25;32(30):10396-407
1	J:160529 Katoh K, Omori Y, Onishi A, Sato S, Kondo M, Furukawa T, Blimp1 suppresses Chx10 expression in differentiating retinal photoreceptor precursors to ensure proper photoreceptor development. J Neurosci. 2010 May 12;30(19):6515-26
2	J:153666 Kawase-Koga Y, Otaegi G, Sun T, Different timings of Dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system. Dev Dyn. 2009 Nov;238(11):2800-12
1*	J:49906 Kenny DA, Jurata LW, Saga Y, Gill GN, Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis. Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11257-62
1*	J:32058 Kilpatrick TJ, Brown A, Lai C, Gassmann M, Goulding M, Lemke G, Expression of the Tyro4/Mek4/Cek4 gene specifically marks a subset of embryonic motor neurons and their muscle targets. Mol Cell Neurosci. 1996 Jan;7(1):62-74
1	J:266544 Kim J, Choi TI, Park S, Kim MH, Kim CH, Lee S, Rnf220 cooperates with Zc4h2 to specify spinal progenitor domains. Development. 2018 Sep 3;145(17):dev165340
2	J:221657 Kong JH, Yang L, Dessaud E, Chuang K, Moore DM, Rohatgi R, Briscoe J, Novitch BG, Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling. Dev Cell. 2015 May 26;33(4):373-87
1	J:195163 Lacombe J, Hanley O, Jung H, Philippidou P, Surmeli G, Grinstein J, Dasen JS, Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons. PLoS Genet. 2013 Jan;9(1):e1003184
1	J:197131 Lanctot AA, Peng CY, Pawlisz AS, Joksimovic M, Feng Y, Spatially dependent dynamic MAPK modulation by the nde1-lis1-brap complex patterns Mammalian CNS. Dev Cell. 2013 May 13;25(3):241-55
1	J:255020 Lee H, Kim M, Kim N, Macfarlan T, Pfaff SL, Mastick GS, Song MR, Slit and Semaphorin signaling governed by Islet transcription factors positions motor neuron somata within the neural tube. Exp Neurol. 2015 Jul;269:17-27
1	J:203926 Lee H, Song MR, The structural role of radial glial endfeet in confining spinal motor neuron somata is controlled by the Reelin and Notch pathways. Exp Neurol. 2013 Nov;249:83-94
2	J:328860 Lee S, Lee B, Joshi K, Pfaff SL, Lee JW, Lee SK, A regulatory network to segregate the identity of neuronal subtypes. Dev Cell. 2008 Jun;14(6):877-89
2	J:155064 Lee S, Lee B, Lee JW, Lee SK, Retinoid signaling and neurogenin2 function are coupled for the specification of spinal motor neurons through a chromatin modifier CBP. Neuron. 2009 Jun 11;62(5):641-54
1	J:96957 Lee SK, Jurata LW, Nowak R, Lettieri K, Kenny DA, Pfaff SL, Gill GN, The LIM domain-only protein LMO4 is required for neural tube closure. Mol Cell Neurosci. 2005 Feb;28(2):205-14
1	J:169530 Li J, Wang C, Pan Y, Bai Z, Wang B, Increased proteolytic processing of full-length Gli2 transcription factor reduces the hedgehog pathway activity in vivo. Dev Dyn. 2011 Apr;240(4):766-74
1	J:100187 Li S, Misra K, Matise MP, Xiang M, Foxn4 acts synergistically with Mash1 to specify subtype identity of V2 interneurons in the spinal cord. Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10688-93
1	J:213871 Li X, Liu Z, Qiu M, Yang Z, Sp8 plays a supplementary role to Pax6 in establishing the pMN/p3 domain boundary in the spinal cord. Development. 2014 Jul;141(14):2875-84
3	J:178050 Liang X, Song MR, Xu Z, Lanuza GM, Liu Y, Zhuang T, Chen Y, Pfaff SL, Evans SM, Sun Y, Isl1 is required for multiple aspects of motor neuron development. Mol Cell Neurosci. 2011 Jul;47(3):215-22
1	J:332369 Liau ES, Jin S, Chen YC, Liu WS, Calon M, Nedelec S, Nie Q, Chen JA, Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons. Nat Commun. 2023 Jan 3;14(1):46
1	J:101029 Lieberam I, Agalliu D, Nagasawa T, Ericson J, Jessell TM, A Cxcl12-CXCR4 chemokine signaling pathway defines the initial trajectory of mammalian motor axons. Neuron. 2005 Sep 1;47(5):667-79
1	J:57673 Lin CR, Kioussi C, O'Connell S, Briata P, Szeto D, Liu F, Izpisua-Belmonte JC, Rosenfeld MG, Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis. Nature. 1999 Sep 16;401(6750):279-82
1	J:98800 Liu A, Wang B, Niswander LA, Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors. Development. 2005 Jul;132(13):3103-11
1	J:246467 Liu W, Cvekl A, Six3 in a small population of progenitors at E8.5 is required for neuroretinal specification via regulating cell signaling and survival in mice. Dev Biol. 2017 Aug 01;428(1):164-175
1	J:343069 Lodge EJ, Barrell WB, Liu KJ, Andoniadou CL, The Fuzzy planar cell polarity protein (FUZ), necessary for primary cilium formation, is essential for pituitary development. J Anat. 2023 Oct 4;
1*	J:75868 Lu QR, Sun T, Zhu Z, Ma N, Garcia M, Stiles CD, Rowitch DH, Common developmental requirement for olig function indicates a motor neuron/oligodendrocyte connection. Cell. 2002 Apr 5;109(1):75-86
2	J:160874 Luria V, Laufer E, Lateral motor column axons execute a ternary trajectory choice between limb and body tissues. Neural Dev. 2007;2:13
2	J:221029 Ma YC, Song MR, Park JP, Henry Ho HY, Hu L, Kurtev MV, Zieg J, Ma Q, Pfaff SL, Greenberg ME, Regulation of motor neuron specification by phosphorylation of neurogenin 2. Neuron. 2008 Apr 10;58(1):65-77
1	J:311909 Machado CB, Kanning KC, Kreis P, Stevenson D, Crossley M, Nowak M, Iacovino M, Kyba M, Chambers D, Blanc E, Lieberam I, Reconstruction of phrenic neuron identity in embryonic stem cell-derived motor neurons. Development. 2014 Feb;141(4):784-94
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
2	J:146279 Medina-Martinez O, Amaya-Manzanares F, Liu C, Mendoza M, Shah R, Zhang L, Behringer RR, Mahon KA, Jamrich M, Cell-autonomous requirement for rx function in the mammalian retina and posterior pituitary. PLoS One. 2009;4(2):e4513
1	J:116391 Merchant M, Evangelista M, Luoh SM, Frantz GD, Chalasani S, Carano RA, van Hoy M, Ramirez J, Ogasawara AK, McFarland LM, Filvaroff EH, French DM, de Sauvage FJ, Loss of the serine/threonine kinase fused results in postnatal growth defects and lethality due to progressive hydrocephalus. Mol Cell Biol. 2005 Aug;25(16):7054-68
3	J:153192 Morikawa Y, Hisaoka T, Senba E, Characterization of Foxp2-expressing cells in the developing spinal cord. Neuroscience. 2009 Sep 15;162(4):1150-62
4	J:156251 Morikawa Y, Komori T, Hisaoka T, Senba E, Detailed expression pattern of Foxp1 and its possible roles in neurons of the spinal cord during embryogenesis. Dev Neurosci. 2009;31(6):511-22
2	J:277700 Nam H, Jeon S, An H, Yoo J, Lee HJ, Lee SK, Lee S, Critical roles of ARHGAP36 as a signal transduction mediator of Shh pathway in lateral motor columnar specification. Elife. 2019 Jul 15;8:e46683
1	J:178908 Okano T, Xuan S, Kelley MW, Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea. J Neurosci. 2011 Dec 7;31(49):18104-18
3	J:114817 Olson LE, Tollkuhn J, Scafoglio C, Krones A, Zhang J, Ohgi KA, Wu W, Taketo MM, Kemler R, Grosschedl R, Rose D, Li X, Rosenfeld MG, Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. Cell. 2006 May 5;125(3):593-605
2	J:245216 Osmundsen AM, Keisler JL, Taketo MM, Davis SW, Canonical WNT Signaling Regulates the Pituitary Organizer and Pituitary Gland Formation. Endocrinology. 2017 Oct 01;158(10):3339-3353
1	J:81765 Pabst O, Rummelies J, Winter B, Arnold HH, Targeted disruption of the homeobox gene Nkx2.9 reveals a role in development of the spinal accessory nerve. Development. 2003 Mar;130(6):1193-202
1	J:193399 Park S, Lee C, Sabharwal P, Zhang M, Meyers CL, Sockanathan S, GDE2 promotes neurogenesis by glycosylphosphatidylinositol-anchor cleavage of RECK. Science. 2013 Jan 18;339(6117):324-8
1	J:215309 Patterson ES, Waller LE, Kroll KL, Geminin loss causes neural tube defects through disrupted progenitor specification and neuronal differentiation. Dev Biol. 2014 Sep 1;393(1):44-56
2	J:132095 Peng CY, Yajima H, Burns CE, Zon LI, Sisodia SS, Pfaff SL, Sharma K, Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord. Neuron. 2007 Mar 15;53(6):813-27
1*	J:31131 Pfaff SL, Mendelsohn M, Stewart CL, Edlund T, Jessell TM, Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation. Cell. 1996 Jan 26;84(2):309-20
1	J:197494 Philippidou P, Walsh CM, Aubin J, Jeannotte L, Dasen JS, Sustained Hox5 gene activity is required for respiratory motor neuron development. Nat Neurosci. 2012 Dec;15(12):1636-44
4*	J:137603 Pontecorvi M, Goding CR, Richardson WD, Kessaris N, Expression of Tbx2 and Tbx3 in the developing hypothalamic-pituitary axis. Gene Expr Patterns. 2008 Jul;8(6):411-7
1*	J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20
1	J:143958 Qi Y, Ranish JA, Zhu X, Krones A, Zhang J, Aebersold R, Rose DW, Rosenfeld MG, Carriere C, Atbf1 is required for the Pit1 gene early activation. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2481-6
1*	J:122509 Raetzman LT, Cai JX, Camper SA, Hes1 is required for pituitary growth and melanotrope specification. Dev Biol. 2007 Apr 15;304(2):455-66
2	J:79850 Raetzman LT, Ward R, Camper SA, Lhx4 and Prop1 are required for cell survival and expansion of the pituitary primordia. Development. 2002 Sep;129(18):4229-39
1	J:188151 Repetto E, Briata P, Kuziner N, Harfe BD, McManus MT, Gherzi R, Rosenfeld MG, Trabucchi M, Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP. PLoS Genet. 2012 Jul;8(7):e1002823
1	J:188384 Rousso DL, Pearson CA, Gaber ZB, Miquelajauregui A, Li S, Portera-Cailliau C, Morrisey EE, Novitch BG, Foxp-mediated suppression of N-cadherin regulates neuroepithelial character and progenitor maintenance in the CNS. Neuron. 2012 Apr 26;74(2):314-30
1	J:235958 Rousso DL, Qiao M, Kagan RD, Yamagata M, Palmiter RD, Sanes JR, Two Pairs of ON and OFF Retinal Ganglion Cells Are Defined by Intersectional Patterns of Transcription Factor Expression. Cell Rep. 2016 May 31;15(9):1930-44
4	J:274433 Roy A, Francius C, Rousso DL, Seuntjens E, Debruyn J, Luxenhofer G, Huber AB, Huylebroeck D, Novitch BG, Clotman F, Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification. Development. 2012 Sep;139(17):3109-19
2	J:178550 Sabharwal P, Lee C, Park S, Rao M, Sockanathan S, GDE2 regulates subtype-specific motor neuron generation through inhibition of Notch signaling. Neuron. 2011 Sep 22;71(6):1058-70
1	J:96345 Sage C, Huang M, Karimi K, Gutierrez G, Vollrath MA, Zhang DS, Garcia-Anoveros J, Hinds PW, Corwin JT, Corey DP, Chen ZY, Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein. Science. 2005 Feb 18;307(5712):1114-8
5	J:142649 Sajedi E, Gaston-Massuet C, Signore M, Andoniadou CL, Kelberman D, Castro S, Etchevers HC, Gerrelli D, Dattani MT, Martinez-Barbera JP, Analysis of mouse models carrying the I26T and R160C substitutions in the transcriptional repressor HESX1 as models for septo-optic dysplasia and hypopituitarism. Dis Model Mech. 2008 Nov;1(4-5):241-54
1	J:52637 Saueressig H, Burrill J, Goulding M, Engrailed-1 and netrin-1 regulate axon pathfinding by association interneurons that project to motor neurons. Development. 1999 Oct;126(19):4201-12
1	J:317827 Sawai A, Pfennig S, Bulajic M, Miller A, Khodadadi-Jamayran A, Mazzoni EO, Dasen JS, PRC1 sustains the integrity of neural fate in the absence of PRC2 function. Elife. 2022 Jan 7;11:e72769
1	J:70697 Scardigli R, Schuurmans C, Gradwohl G, Guillemot F, Crossregulation between Neurogenin2 and Pathways Specifying Neuronal Identity in the Spinal Cord. Neuron. 2001 Aug;31(2):203-17
16*	J:22277 Seidah NG, Barale JC, Marcinkiewicz M, Mattei MG, Day R, Chretien M, The mouse homeoprotein mLIM-3 is expressed early in cells derived from the neuroepithelium and persists in adult pituitary. DNA Cell Biol. 1994 Dec;13(12):1163-80
2	J:51420 Sharma K, Sheng HZ, Lettieri K, Li H, Karavanov A, Potter S, Westphal H, Pfaff SL, LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons. Cell. 1998 Dec 11;95(6):817-28
4	J:44644 Sheng HZ, Moriyama K, Yamashita T, Li H, Potter SS, Mahon KA, Westphal H, Multistep control of pituitary organogenesis. Science. 1997 Dec 5;278(5344):1809-12
2	J:168563 Shi Y, Liu JP, Gdf11 facilitates temporal progression of neurogenesis in the developing spinal cord. J Neurosci. 2011 Jan 19;31(3):883-93
1	J:122940 Shirasaki R, Lewcock JW, Lettieri K, Pfaff SL, FGF as a target-derived chemoattractant for developing motor axons genetically programmed by the LIM code. Neuron. 2006 Jun 15;50(6):841-53
1	J:86868 Simon R, Lufkin T, Postnatal lethality in mice lacking the Sax2 homeobox gene homologous to Drosophila S59/slouch: evidence for positive and negative autoregulation. Mol Cell Biol. 2003 Dec;23(24):9046-60
1	J:119655 Song MR, Shirasaki R, Cai CL, Ruiz EC, Evans SM, Lee SK, Pfaff SL, T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration. Development. 2006 Dec;133(24):4945-55
1	J:152175 Song MR, Sun Y, Bryson A, Gill GN, Evans SM, Pfaff SL, Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity. Development. 2009 Sep;136(17):2923-32
4*	J:36967 Sornson MW, Wu W, Dasen JS, Flynn SE, Norman DJ, O'Connell SM, Gukovsky I, Carriere C, Ryan AK, Miller AP, Zuo L, Gleiberman AS, Andersen B, Beamer WG, Rosenfeld MG, Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism. Nature. 1996 Nov 28;384(6607):327-33
1	J:263775 Stallings CE, Ellsworth BS, Premature Expression of FOXO1 in Developing Mouse Pituitary Results in Anterior Lobe Hypoplasia. Endocrinology. 2018 Aug 1;159(8):2891-2904
1	J:73774 Suh H, Gage PJ, Drouin J, Camper SA, Pitx2 is required at multiple stages of pituitary organogenesis: pituitary primordium formation and cell specification. Development. 2002 Jan;129(2):329-37
1	J:71636 Sun T, Echelard Y, Lu R, Yuk D, Kaing S, Stiles CD, Rowitch DH, Olig bHLH proteins interact with homeodomain proteins to regulate cell fate acquisition in progenitors of the ventral neural tube. Curr Biol. 2001 Sep 18;11(18):1413-20
3	J:50974 Sun T, Pringle NP, Hardy AP, Richardson WD, Smith HK, Pax6 influences the time and site of origin of glial precursors in the ventral neural tube. Mol Cell Neurosci. 1998 Nov;12(4-5):228-39
1	J:53310 Szeto DP, Rodriguez-Esteban C, Ryan AK, O'Connell SM, Liu F, Kioussi C, Gleiberman AS, Izpisua-Belmonte JC, Rosenfeld MG, Role of the Bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development. Genes Dev. 1999 Feb 15;13(4):484-94
6*	J:34314 Szeto DP, Ryan AK, O'Connell SM, Rosenfeld MG, P-OTX: a PIT-1-interacting homeodomain factor expressed during anterior pituitary gland development. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7706-10
1*	J:50517 Takuma N, Sheng HZ, Furuta Y, Ward JM, Sharma K, Hogan BL, Pfaff SL, Westphal H, Kimura S, Mahon KA, Formation of Rathke's pouch requires dual induction from the diencephalon. Development. 1998 Dec;125(23):4835-40
4*	J:297267 Tang Q, Xu M, Xu J, Xie X, Yang H, Gan L, Gfi1-GCE inducible Cre line for hair cell-specific gene manipulation in mouse inner ear. Genesis. 2019 Sep;57(9):e23304
2	J:57339 Thaler J, Harrison K, Sharma K, Lettieri K, Kehrl J, Pfaff SL, Active suppression of interneuron programs within developing motor neurons revealed by analysis of homeodomain factor HB9. Neuron. 1999 Aug;23(4):675-87
1	J:89755 Thaler JP, Koo SJ, Kania A, Lettieri K, Andrews S, Cox C, Jessell TM, Pfaff SL, A postmitotic role for Isl-class LIM homeodomain proteins in the assignment of visceral spinal motor neuron identity. Neuron. 2004 Feb 5;41(3):337-50
2	J:91470 Theriault FM, Roy P, Stifani S, AML1/Runx1 is important for the development of hindbrain cholinergic branchiovisceral motor neurons and selected cranial sensory neurons. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10343-8
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
13	J:134683 Tian G, Singh U, Yu Y, Ellsworth BS, Hemberger M, Geyer R, Stewart MD, Behringer RR, Fundele R, Expression and function of the LIM homeobox containing genes Lhx3 and Lhx4 in the mouse placenta. Dev Dyn. 2008 May;237(5):1517-25
2	J:293140 Toch M, Harris A, Schakman O, Kondratskaya E, Boulland JL, Dauguet N, Debrulle S, Baudouin C, Hidalgo-Figueroa M, Gow A, Glover JC, Tissir F, Clotman F, Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits. Sci Rep. 2020 Jan 22;10(1):996
4	J:66789 Treier M, O'Connell S, Gleiberman A, Price J, Szeto DP, Burgess R, Chuang PT, McMahon AP, Rosenfeld MG, Hedgehog signaling is required for pituitary gland development. Development. 2001 Feb;128(3):377-86
1*	J:34768 Tremblay P, Pituello F, Gruss P, Inhibition of floor plate differentiation by Pax3: evidence from ectopic expression in transgenic mice. Development. 1996 Aug;122(8):2555-67
2	J:198684 Trowe MO, Zhao L, Weiss AC, Christoffels V, Epstein DJ, Kispert A, Inhibition of Sox2-dependent activation of Shh in the ventral diencephalon by Tbx3 is required for formation of the neurohypophysis. Development. 2013 Jun;140(11):2299-309
3	J:147278 Tzchori I, Day TF, Carolan PJ, Zhao Y, Wassif CA, Li L, Lewandoski M, Gorivodsky M, Love PE, Porter FD, Westphal H, Yang Y, LIM homeobox transcription factors integrate signaling events that control three-dimensional limb patterning and growth. Development. 2009 Apr;136(8):1375-85
2	J:71607 Vallstedt A, Muhr J, Pattyn A, Pierani A, Mendelsohn M, Sander M, Jessell TM, Ericson J, Different levels of repressor activity assign redundant and specific roles to Nkx6 genes in motor neuron and interneuron specification. Neuron. 2001 Sep 13;31(5):743-55
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
3*	J:121427 Wang J, Scully K, Zhu X, Cai L, Zhang J, Prefontaine GG, Krones A, Ohgi KA, Zhu P, Garcia-Bassets I, Liu F, Taylor H, Lozach J, Jayes FL, Korach KS, Glass CK, Fu XD, Rosenfeld MG, Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature. 2007 Apr 19;446(7138):882-7
2	J:306250 Wang W, Cho H, Kim D, Park Y, Moon JH, Lim SJ, Yoon SM, McCane M, Aicher SA, Kim S, Emery B, Lee JW, Lee S, Park Y, Lee SK, PRC2 Acts as a Critical Timer That Drives Oligodendrocyte Fate over Astrocyte Identity by Repressing the Notch Pathway. Cell Rep. 2020 Sep 15;32(11):108147
4	J:321501 Wang W, Cho H, Lee JW, Lee SK, The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development. Nat Commun. 2022 Feb 17;13(1):958
1	J:92940 Wang W, Grimmer JF, Van De Water TR, Lufkin T, Hmx2 and Hmx3 homeobox genes direct development of the murine inner ear and hypothalamus and can be functionally replaced by Drosophila Hmx. Dev Cell. 2004 Sep;7(3):439-53
1	J:65759 Wang W, Lufkin T, The murine otp homeobox gene plays an essential role in the specification of neuronal cell lineages in the developing hypothalamus. Dev Biol. 2000 Nov 15;227(2):432-49
1	J:166929 Wang Y, Martin JF, Bai CB, Direct and indirect requirements of Shh/Gli signaling in early pituitary development. Dev Biol. 2010 Dec 15;348(2):199-209
1	J:206319 Welcker JE, Hernandez-Miranda LR, Paul FE, Jia S, Ivanov A, Selbach M, Birchmeier C, Insm1 controls development of pituitary endocrine cells and requires a SNAG domain for function and for recruitment of histone-modifying factors. Development. 2013 Dec;140(24):4947-58
1	J:171463 Wong EY, Wang XA, Mak SS, Sae-Pang JJ, Ling KW, Fritzsch B, Sham MH, Hoxb3 negatively regulates Hoxb1 expression in mouse hindbrain patterning. Dev Biol. 2011 Apr 15;352(2):382-92
3	J:89175 Woodside KJ, Shen H, Muntzel C, Daller JA, Sommers CL, Love PE, Expression of Dlx and Lhx family homeobox genes in fetal thymus and thymocytes. Gene Expr Patterns. 2004 May;4(3):315-20
1	J:130489 Wu Y, Wang G, Scott SA, Capecchi MR, Hoxc10 and Hoxd10 regulate mouse columnar, divisional and motor pool identity of lumbar motoneurons. Development. 2008 Jan;135(1):171-82
12*	J:261409 Xu M, Xie X, Dong X, Liang G, Gan L, Generation and characterization of Lhx3(GFP) reporter knockin and Lhx3(loxP) conditional knockout mice. Genesis. 2018 Apr;56(4):e23098
1	J:287680 Yamamoto H, Kon T, Omori Y, Furukawa T, Functional and Evolutionary Diversification of Otx2 and Crx in Vertebrate Retinal Photoreceptor and Bipolar Cell Development. Cell Rep. 2020 Jan 21;30(3):658-671.e5
1*	J:224892 Yan Y, Wladyka C, Fujii J, Sockanathan S, Prdx4 is a compartment-specific H2O2 sensor that regulates neurogenesis by controlling surface expression of GDE2. Nat Commun. 2015;6:7006
2	J:290593 Yen YP, Hsieh WF, Tsai YY, Lu YL, Liau ES, Hsu HC, Chen YC, Liu TC, Chang M, Li J, Lin SP, Hung JH, Chen JA, Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity. Elife. 2018 Oct 12;7:e38080
1	J:132890 Yip YP, Capriotti C, Drill E, Tsai LH, Yip JW, Cdk5 selectively affects the migration of different populations of neurons in the developing spinal cord. J Comp Neurol. 2007 Jul 10;503(2):297-307
1	J:264522 Youngblood JL, Coleman TF, Davis SW, Regulation of Pituitary Progenitor Differentiation by beta-Catenin. Endocrinology. 2018 Sep 1;159(9):3287-3305
1	J:143585 Yu W, McDonnell K, Taketo MM, Bai CB, Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner. Development. 2008 Nov;135(22):3687-96
12*	J:24499 Zhadanov AB, Bertuzzi S, Taira M, Dawid IB, Westphal H, Expression pattern of the murine LIM class homeobox gene Lhx3 in subsets of neural and neuroendocrine tissues. Dev Dyn. 1995 Apr;202(4):354-64
3	J:80253 Zhang Y, Mori T, Takaki H, Takeuch M, Iseki K, Hagino S, Murakawa M, Yokoya S, Wanaka A, Comparison of the expression patterns of two LIM-homeodomain genes, Lhx6 and L3/Lhx8, in the developing palate. Orthod Craniofac Res. 2002 May;5(2):65-70
1	J:182725 Zhao L, Zevallos SE, Rizzoti K, Jeong Y, Lovell-Badge R, Epstein DJ, Disruption of SoxB1-dependent Sonic hedgehog expression in the hypothalamus causes septo-optic dysplasia. Dev Cell. 2012 Mar 13;22(3):585-96
1	J:157264 Zhao Y, Mailloux CM, Hermesz E, Palkovits M, Westphal H, A role of the LIM-homeobox gene Lhx2 in the regulation of pituitary development. Dev Biol. 2010 Jan 15;337(2):313-23
6*	J:119270 Zhao Y, Morales DC, Hermesz E, Lee WK, Pfaff SL, Westphal H, Reduced expression of the LIM-homeobox gene Lhx3 impairs growth and differentiation of Rathke's pouch and increases cell apoptosis during mouse pituitary development. Mech Dev. 2006 Aug;123(8):605-13
1*	J:63686 Zhou Y, Yamamoto M, Engel JD, GATA2 is required for the generation of V2 interneurons. Development. 2000 Sep;127(17):3829-38
2	J:287133 Zhu X, Tollkuhn J, Taylor H, Rosenfeld MG, Notch-Dependent Pituitary SOX2(+) Stem Cells Exhibit a Timed Functional Extinction in Regulation of the Postnatal Gland. Stem Cell Reports. 2015 Dec 8;5(6):1196-1209
1	J:217063 Zou M, Luo H, Xiang M, Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord. Dev Dyn. 2015 Jan;244(1):86-97