Gene Expression Literature Summary

• Symbol: Thpo
• Name: thrombopoietin
• ID: MGI:101875

14 matching records from 14 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7	E8	E9	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16.5	E18	E18.5	E	P
In situ RNA (section)										1		1		1		1			1		1
In situ RNA (whole mount)																1
In situ reporter (knock in)																					1
Northern blot																				1	1
Western blot							1				1				1			1			1
RT-PCR	1	1	1	2	2	1	3	2	1	1	2	1	2	2	1	1	1	1	1		4
cDNA clones																				1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Thpo  thrombopoietin   (Synonyms: Mpllg, myeloproliferative leukemia virus oncogene ligand, TPO, TPO-1, TPO-2, TPO-3, TPO-4)
Results	Reference
5*	J:159378 Chou S, Lodish HF, Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7799-804
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
10*	J:96497 Ehrenreich H, Hasselblatt M, Knerlich F, von Ahsen N, Jacob S, Sperling S, Woldt H, Vehmeyer K, Nave KA, Siren AL, A hematopoietic growth factor, thrombopoietin, has a proapoptotic role in the brain. Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):862-7
1	J:282733 Gerlini R, Amendola E, Conte A, Valente V, Tornincasa M, Credendino SC, Cammarota F, Gentile C, Di Guida L, Paladino S, De Vita G, Fusco A, Pierantoni GM, Double knock-out of Hmga1 and Hipk2 genes causes perinatal death associated to respiratory distress and thyroid abnormalities in mice. Cell Death Dis. 2019 Oct 3;10(10):747
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
5*	J:163547 Ivanova A, Wuerfel J, Zhang J, Hoffmann O, Ballmaier M, Dame C, Expression pattern of the thrombopoietin receptor (Mpl) in the murine central nervous system. BMC Dev Biol. 2010;10:77
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
7	J:41395 Nomura S, Ogami K, Kawamura K, Tsukamoto I, Kudo Y, Kanakura Y , Kitamura Y , Miyazaki H , Kato T, Cellular localization of thrombopoietin mRNA in the liver by in situ hybridization. Exp Hematol. 1997 Jul;25(7):565-72
2*	J:124109 Petit-Cocault L, Volle-Challier C, Fleury M, Peault B, Souyri M, Dual role of Mpl receptor during the establishment of definitive hematopoiesis. Development. 2007 Aug;134(16):3031-40
2*	J:174962 Sugiyama D, Kulkeaw K, Mizuochi C, Horio Y, Okayama S, Hepatoblasts comprise a niche for fetal liver erythropoiesis through cytokine production. Biochem Biophys Res Commun. 2011 Jul 1;410(2):301-6
2	J:63425 Tamura K, Sudo T, Senftleben U, Dadak AM, Johnson R, Karin M, Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis. Cell. 2000 Jul 21;102(2):221-31
8*	J:82323 Xie X, Chan RJ, Johnson SA, Starr M, McCarthy J, Kapur R, Yoder MC, Thrombopoietin promotes mixed lineage and megakaryocytic colony-forming cell growth but inhibits primitive and definitive erythropoiesis in cells isolated from early murine yolk sacs. Blood. 2003 Feb 15;101(4):1329-35
1	J:30031 Yan XQ, Lacey D, Fletcher F, Hartley C, McElroy P, Sun Y, Xia M, Mu S, Saris C, Hill D, Hawlwy RG, McNiece IK, Chronic exposure to retroviral vector encoded MGDF (mpl-ligand) induces lineage-specific growth and differentiation of megakaryocytes in mice. Blood. 1995 Dec 1;86(11):4025-33
1*	J:236440 You L, Yan K, Zou J, Zhao H, Bertos NR, Park M, Wang E, Yang XJ, The chromatin regulator Brpf1 regulates embryo development and cell proliferation. J Biol Chem. 2015 May 1;290(18):11349-64