Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 9.0.0)

Enables several functions, including DNA binding activity; RNA binding activity; and promoter-specific chromatin binding activity. Involved in several processes, including axo-dendritic protein transport; negative regulation of smooth muscle cell differentiation; and protein localization to presynapse. Acts upstream of or within several processes, including glycerolipid metabolic process; nervous system development; and regulation of gene expression. Located in cytosol; heterochromatin; and nucleus. Is active in asymmetric synapse. Is expressed in several structures, including alimentary system; blastocyst-stage conceptus; nervous system; paraxial mesenchyme; and sensory organ. Used to study Rett syndrome. Human ortholog(s) of this gene implicated in Rett syndrome; autistic disorder; gastrointestinal system disease; severe congenital encephalopathy due to MECP2 mutation; and syndromic X-linked intellectual disability (multiple). Orthologous to human MECP2 (methyl-CpG binding protein 2).

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Gene Ontology Evidence Code Abbreviations:

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