Automated description from the Alliance of Genome Resources (Release 6.0.0)
Predicted to enable integrin binding activity. Predicted to be involved in several processes, including axon guidance; hemidesmosome assembly; and morphogenesis of a polarized epithelium. Predicted to act upstream of or within cell adhesion. Located in basement membrane. Part of laminin-5 complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skin. Used to study junctional epidermolysis bullosa and junctional epidermolysis bullosa non-Herlitz type. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa and lung small cell carcinoma. Orthologous to human LAMA3 (laminin subunit alpha 3).