Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 9.0.0)

Enables DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and histone acetyltransferase activity. Involved in several processes, including negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway; regulation of gene expression; and regulation of insulin secretion. Acts upstream of or within circadian rhythm; gene expression; and positive regulation of transcription by RNA polymerase II. Located in chromatoid body and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; ear; extraembryonic component; genitourinary system; and nervous system. Used to study bipolar disorder; diabetes mellitus; and sleep disorder. Human ortholog(s) of this gene implicated in Alzheimer's disease and alcohol use disorder. Orthologous to human CLOCK (clock circadian regulator).

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Gene Ontology Evidence Code Abbreviations:

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