Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables histone methyltransferase binding activity; promoter-specific chromatin binding activity; and transcription cis-regulatory region binding activity. Involved in gene expression and regulation of lymphocyte differentiation. Acts upstream of or within several processes, including circulatory system development; eye morphogenesis; and regulation of gene expression. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; retina; and skin. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and lung adenocarcinoma. Orthologous to human PRDM1 (PR/SET domain 1).