Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable pore-forming activity and protein homodimerization activity. Acts upstream of or within defense response to bacterium and disruption of plasma membrane integrity in another organism. Located in secretory granule. Is expressed in embryo; hindgut diverticulum; node; and notochord. Orthologous to several human genes including DEFA1 (defensin alpha 1); DEFA1B (defensin alpha 1B); and DEFA3 (defensin alpha 3).