Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables identical protein binding activity. Acts upstream of with a negative effect on canonical NF-kappaB signal transduction and regulation of non-canonical NF-kappaB signal transduction. Acts upstream of or within several processes, including natural killer cell mediated cytotoxicity; regulation of stress-activated MAPK cascade; and removal of superoxide radicals. Located in mitochondrion and myelin sheath. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblC. Orthologous to human PRDX1 (peroxiredoxin 1).