Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable identical protein binding activity and voltage-gated chloride channel activity. Acts upstream of or within endocytosis. Located in apical part of cell and endosome. Is expressed in several structures, including early conceptus; heart; metanephros; oocyte; and stomach. Used to study Dent disease. Human ortholog(s) of this gene implicated in Dent disease; X-linked nephrolithiasis type I; X-linked recessive hypophosphatemic rickets; and low molecular weight proteinuria with hypercalciuric nephrocalcinosis. Orthologous to human CLCN5 (chloride voltage-gated channel 5).