Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 8.3.0)

Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; cholesterol binding activity; and promoter-specific chromatin binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including cellular response to cholesterol; neurogenesis; and regulation of primary metabolic process. Located in endoplasmic reticulum membrane and nucleus. Part of protein-containing complex. Is expressed in several structures, including central nervous system; early conceptus; female reproductive system; head mesenchyme; and urinary system. Used to study hepatocellular carcinoma and type 2 diabetes mellitus. Orthologous to human NFE2L1 (NFE2 like bZIP transcription factor 1).

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Gene Ontology Evidence Code Abbreviations:

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