Automated description from the Alliance of Genome Resources (Release 9.0.0)
Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and lncRNA binding activity. Contributes to promoter-specific chromatin binding activity. Involved in several processes, including DNA metabolic process; negative regulation of miRNA transcription; and positive regulation of DNA metabolic process. Acts upstream of or within several processes, including camera-type eye morphogenesis; regulation of gene expression; and regulatory T cell differentiation. Located in nucleus. Part of nucleus; ribonucleoprotein complex; and transcription regulator complex. Is active in chromatin. Is expressed in several structures, including 4-8 cell stage conceptus; blastocyst-stage conceptus; early embryo; neural ectoderm; and reproductive system. Used to study pleuropulmonary blastoma. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human YY1 (YY1 transcription factor).
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