Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables protein-disulfide reductase activity. Acts upstream of or within cell redox homeostasis; negative regulation of protein export from nucleus; and negative regulation of transcription by RNA polymerase II. Located in cytosol and nucleus. Is expressed in several structures, including central nervous system; skeleton; and submandibular gland primordium. Orthologous to human TXN (thioredoxin).