Automated description from the Alliance of Genome Resources (Release 8.0.0)
Enables thiopurine S-methyltransferase activity. Predicted to be involved in xenobiotic metabolic process. Predicted to be located in cytoplasm. Is expressed in metanephros. Used to study poor metabolism of thiopurines. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; alopecia; leukopenia; and poor metabolism of thiopurines 1. Orthologous to human TPMT (thiopurine S-methyltransferase).
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