Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables tryptophan 5-monooxygenase activity. Involved in platelet degranulation; regulation of hemostasis; and serotonin biosynthetic process. Acts upstream of or within bone remodeling; mammary gland alveolus development; and positive regulation of fat cell differentiation. Located in cytoplasm. Is expressed in several structures, including central nervous system; gut; ovary; retina; and trunk. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; attention deficit hyperactivity disorder; borderline personality disorder; depressive disorder (multiple); and scoliosis. Orthologous to human TPH1 (tryptophan hydroxylase 1).