Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables ABC-type peptide antigen transporter activity and MHC class I protein binding activity. Acts upstream of or within defense response. Located in mitochondrion. Is expressed in cranium; early conceptus; limb; nervous system; and oocyte. Human ortholog(s) of this gene implicated in several diseases, including MHC class I deficiency; autoimmune disease (multiple); bronchial disease (multiple); diffuse scleroderma; and lung disease (multiple). Orthologous to human TAP1 (transporter 1, ATP binding cassette subfamily B member).