Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in cardiac muscle cell myoblast differentiation; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including chordate embryonic development; circulatory system development; and embryonic morphogenesis. Located in cytoplasm and nucleus. Part of chromatin. Is expressed in several structures, including egg cylinder; embryo mesenchyme; future spinal cord; genitourinary system; and mesoderm. Human ortholog(s) of this gene implicated in neural tube defect. Orthologous to human TBXT (T-box transcription factor T).