Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables pre-mRNA binding activity. Acts upstream of or within regulation of alternative mRNA splicing, via spliceosome. Located in nuclear speck. Part of spliceosomal complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system gland; and retina. Used to study myelodysplastic syndrome. Human ortholog(s) of this gene implicated in acute myeloid leukemia; congestive heart failure; hepatocellular carcinoma; and myelodysplastic syndrome. Orthologous to human SRSF2 (serine and arginine rich splicing factor 2).