Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables ferric iron binding activity; protein homodimerization activity; and ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Involved in 2'-deoxyribonucleotide biosynthetic process; protein heterotetramerization; and ribonucleoside diphosphate metabolic process. Acts upstream of or within deoxyribonucleotide metabolic process. Part of ribonucleoside-diphosphate reductase complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RRM2 (ribonucleotide reductase regulatory subunit M2).