Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 8.3.0)

Enables G protein activity; GTP binding activity; and GTP-dependent protein binding activity. Involved in several processes, including cell surface receptor signaling pathway; nervous system development; and regulation of cell migration. Acts upstream of or within several processes, including actin filament polymerization; neuron differentiation; and regulation of intracellular signal transduction. Located in several cellular components, including kinocilium; pericentriolar material; and ruffle membrane. Is active in glutamatergic synapse; synaptic membrane; and synaptic vesicle membrane. Is expressed in several structures, including central nervous system; early conceptus; eye; genitourinary system; and spinal component of peripheral nervous system. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 48; colorectal cancer (multiple); lung cancer; and pancreatic adenocarcinoma. Orthologous to human RAC1 (Rac family small GTPase 1).

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Gene Ontology Evidence Code Abbreviations:

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