Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables chondroitin sulfate binding activity; heparin binding activity; and protein tyrosine phosphatase activity. Involved in several processes, including negative regulation of dendritic spine development; negative regulation of neuron projection development; and regulation of postsynaptic density assembly. Acts upstream of or within central nervous system development and establishment of endothelial intestinal barrier. Located in plasma membrane. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and presynaptic membrane. Is expressed in several structures, including adipose tissue; genitourinary system; gut; nervous system; and sensory organ. Orthologous to human PTPRS (protein tyrosine phosphatase receptor type S).