Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables protein tyrosine phosphatase activity. Involved in integrin-mediated signaling pathway; modulation of chemical synaptic transmission; and regulation of focal adhesion assembly. Acts upstream of or within insulin receptor signaling pathway. Located in focal adhesion and membrane. Is active in Schaffer collateral - CA1 synapse and synaptic membrane. Is expressed in several structures, including adrenal gland; central nervous system; extraembryonic component; future brain; and genitourinary system. Orthologous to human PTPRA (protein tyrosine phosphatase receptor type A).