Automated description from the Alliance of Genome Resources (Release 5.4.0)
Enables peptidase activity. Acts upstream of or within liver development; negative regulation of blood coagulation; and regulation of circulating fibrinogen levels. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Predicted to be part of serine-type endopeptidase complex. Predicted to be active in extracellular space. Is expressed in embryo; liver; and liver lobe. Human ortholog(s) of this gene implicated in several diseases, including antiphospholipid syndrome; central retinal vein occlusion; placental abruption; thrombophilia (multiple); and toxic shock syndrome. Orthologous to human PROC (protein C, inactivator of coagulation factors Va and VIIIa).