Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 8.3.0)

Enables several functions, including ATP hydrolysis activity; ATPase-coupled intramembrane lipid transporter activity; and xenobiotic transmembrane transporter activity. Involved in several processes, including lipid translocation; terpenoid transport; and xenobiotic transport across blood-brain barrier. Acts upstream of or within several processes, including aldosterone secretion; heart development; and neural tissue regeneration. Located in intercellular canaliculus. Is active in apical plasma membrane. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and integumental system. Used to study inflammatory bowel disease 13. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); drug dependence (multiple); human immunodeficiency virus infectious disease (multiple); inflammatory bowel disease (multiple); and leukemia (multiple). Orthologous to human ABCB1 (ATP binding cassette subfamily B member 1).

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Gene Ontology Evidence Code Abbreviations:

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