Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables 6-phosphofructokinase activity and identical protein binding activity. Involved in canonical glycolysis. Acts upstream of or within glucose homeostasis; polysaccharide catabolic process; and positive regulation of insulin secretion. Located in sperm principal piece. Is active in cytosol. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and musculoskeletal system. Used to study glycogen storage disease VII. Human ortholog(s) of this gene implicated in glycogen storage disease VII. Orthologous to human PFKM (phosphofructokinase, muscle).