Automated description from the Alliance of Genome Resources (Release 6.0.0)
Enables 6-phosphofructokinase activity. Involved in glycolytic process through fructose-6-phosphate. Acts upstream of or within fructose 6-phosphate metabolic process; negative regulation of insulin secretion; and response to glucose. Located in cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; musculoskeletal system; and sensory organ. Orthologous to human PFKL (phosphofructokinase, liver type).