Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables enzyme binding activity. Involved in mitotic telomere maintenance via semi-conservative replication and replication fork processing. Acts upstream of or within base-excision repair, gap-filling; cellular response to xenobiotic stimulus; and negative regulation of transcription by RNA polymerase II. Located in male germ cell nucleus; nuclear lamina; and replication fork. Part of cyclin-dependent protein kinase holoenzyme complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; musculoskeletal system; and sensory organ. Human ortholog(s) of this gene implicated in ataxia-telangiectasia-like disorder-2. Orthologous to human PCNA (proliferating cell nuclear antigen).