Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including face morphogenesis; odontogenesis; and regulation of odontogenesis. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of transcription regulator complex. Is expressed in several structures, including alimentary system; branchial arch; embryo mesenchyme; genitourinary system; and nose. Used to study tooth agenesis. Human ortholog(s) of this gene implicated in tooth agenesis. Orthologous to human PAX9 (paired box 9).