Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 8.1.0)

Enables several functions, including anion binding activity; heme binding activity; and nitric-oxide synthase activity. Involved in several processes, including negative regulation of macromolecule metabolic process; nitric oxide biosynthetic process; and peptidyl-cysteine S-nitrosylation. Acts upstream of or within several processes, including cellular response to type II interferon; response to bacterium; and superoxide metabolic process. Located in cortical cytoskeleton and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; brain; enteric nervous system; extraembryonic component; and genitourinary system. Used to study Alzheimer's disease and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including dementia (multiple); hypertension (multiple); malaria; pulmonary tuberculosis; and type 2 diabetes mellitus. Orthologous to human NOS2 (nitric oxide synthase 2).

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Gene Ontology Evidence Code Abbreviations:

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