Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 8.2.0)

Enables transmembrane receptor protein tyrosine kinase activator activity. Involved in several processes, including circadian rhythm; neurotrophin TRK receptor signaling pathway; and positive regulation of intracellular signal transduction. Acts upstream of or within several processes, including cell surface receptor signaling pathway; positive regulation of cell projection organization; and positive regulation of protein modification process. Located in extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Used to study hereditary sensory and autonomic neuropathy type 5. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; end stage renal disease; hereditary sensory and autonomic neuropathy type 5; interstitial cystitis; and opiate dependence (multiple). Orthologous to human NGF (nerve growth factor).

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Gene Ontology Evidence Code Abbreviations:

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