Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 8.3.0)

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including NK T cell proliferation; positive regulation of macromolecule metabolic process; and positive regulation of metanephric cap mesenchymal cell proliferation. Acts upstream of or within several processes, including cellular response to interferon-alpha; positive regulation of apoptotic process; and regulation of transcription by RNA polymerase II. Located in several cellular components, including euchromatin; nuclear body; and perinuclear region of cytoplasm. Part of Myc-Max complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; sensory organ; and urinary system. Used to study Burkitt lymphoma; autosomal dominant polycystic kidney disease; breast cancer; hepatocellular carcinoma; and pancreatic carcinoma. Human ortholog(s) of this gene implicated in several diseases, including angiosarcoma; carcinoma (multiple); demyelinating disease; hematologic cancer (multiple); and prostate cancer (multiple). Orthologous to human MYC (MYC proto-oncogene, bHLH transcription factor).

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Gene Ontology Evidence Code Abbreviations:

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