Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 9.0.0)

Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; p53 binding activity; and transcription coregulator activity. Predicted to be involved in several processes, including DNA damage response, signal transduction by p53 class mediator; negative regulation of cell adhesion mediated by integrin; and negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Located in apical plasma membrane and cell surface. Is expressed in several structures, including alimentary system; brain; exocrine system; genitourinary system; and respiratory system. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant tubulointerstitial kidney disease 2; biliary tract benign neoplasm; dry eye syndrome; mucinous adenocarcinoma; and pancreatic cancer (multiple). Orthologous to human MUC1 (mucin 1, cell surface associated).

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Gene Ontology Evidence Code Abbreviations:

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