Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and bHLH transcription factor binding activity. Involved in several processes, including T follicular helper cell differentiation; negative regulation of T-helper cell differentiation; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including regulation of transcription by RNA polymerase II; somatic stem cell population maintenance; and spongiotrophoblast differentiation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and musculoskeletal system. Orthologous to human ASCL2 (achaete-scute family bHLH transcription factor 2).